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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Scientist examines Western blots in the laboratory.

Novel stem cell therapy repairs irreversible corneal damage in clinical trial

A clinical trial that tested an experimental stem cell treatment for blinding cornea injuries found the treatment was feasible and safe in 14 patients, and there was a high proportion of complete or partial success.
eye image

Mount Sinai-led research team identifies underlying mechanisms of age-related dysfunction in glands crucial to eye function

A team led by researchers at Mount Sinai has identified in mice a potential therapeutic target for dry eye disease.
mouse

New study uncovers how genes influence retinal aging and brain health

Researchers at the Jackson Laboratories used mice with nine different genetic backgrounds to identify factors influencing eye aging, paving the way for eye-based diagnostics for neurodegenerative diseases
Head-mounted robotic device for eye surgery.

Early study shows promise for retinal-surgery robot invented at the University of Utah

Researchers create a new robotic surgery device that aims to give surgeons “superhuman” hands, accounting for patients’ breathing and eye movements, along with their own involuntary hand tremors, while they work on retinal tissues.
Diagram of the eye showing location of the lens.

FAU lands $1.9 million NIH grant for novel way to treat degenerative disease

Florida Atlantic University researchers Lisa A. Brennan and Marc Kantorow will determine the novel mechanisms that convert immature eye lens precursor cells into functional transparent cells.
optic nerves

Nerve regrowth in sight

UConn scientists led by Ephraim Trakhtenberg regrew optic nerves in mice through eye injections of fibronectin peptides (pieces of the larger protein).

UC Irvine-co-led study finds DNA damage is key factor in age-related macular degeneration

Study reveals how DNA damage, a hallmark of aging, compromises the retina’s function and accelerates vision loss. Targeting specific retinal cell types could lead to treatments that slow or stop progression.
Eye illustration

ARPA-H announces funding for development of eye transplantation

ARPA-H announced the teams to receive awards from its Transplantation of Human Eye Allografts (THEA) program.

CRISPR gene editing promising for blinding disease retinitis pigmentosa

National Eye Institute-funded scientists using gene editing corrected a mutation in a mouse model of retinitis pigmentosa, an inherited blinding eye disorder. The gene editing strategy restored production of rhodopsin, and retinal function and structure
Zebrafish, imaged via fluorescence confocal microscopy

New model of neuronal circuit provides insight on eye movement

Working with week-old zebrafish larva, researchers at Weill Cornell Medicine and colleagues decoded how the connections formed by a network of neurons in the brainstem guide the fishes’ gaze.