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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Cells with red nuclei and long green processes

Scientists unravel the function of a sight-saving growth factor

Researchers at the National Eye Institute (NEI) have determined how certain short protein fragments, called peptides, can protect neuronal cells found in the light-sensing retina layer at the back of the eye.
Box of tissues

What makes us sneeze?

A team led by researchers at Washington University School of Medicine in St. Louis has identified, in mice, specific cells and proteins that control the sneeze reflex.

As novel sights become familiar, different brain rhythms, neurons take over

A new study by researchers at MIT’s Picower Institute for Learning and Memory substantially advances understanding of how a mammalian brain enables “visual recognition memory.”
Image of brain cells with "sparks" of red and yellow

Brain tumors caused by normal neuron activity in mice predisposed to such tumors

A study by researchers at Washington University School of Medicine in St. Louis and Stanford University School of Medicine shows that the normal day-to-day activity of neurons can drive the formation and growth of brain tumors.

Vision researchers at Wayne State discover new therapy to treat eye infections

Researchers at the Wayne State University School of Medicine have discovered that a metabolite called itaconate produced during cellular metabolism plays a role in protecting the eye from abnormal inflammation during infection.
Slice of OCT image hovers over 3D segmentation of retinal cells

AI Spots Individual Neurons in the Eye Better than Human Experts

A new combination of optical coherence tomography (OCT), adaptive optics and deep neural networks should enable better diagnosis and monitoring for neuron-damaging eye and brain diseases like glaucoma.
city street at night as seen by a person with normal vision

A new theory for what’s happening in the brain when something looks familiar

University of Pennsylvania researchers propose a new theory for how the brain understands the level of activation expected from a sensory input and corrects for it, leaving behind the signal for familiarity.

Neural Implant Monitors Multiple Brain Areas at Once, Provides New Neuroscience Insights

Researchers at UCSD have developed a neural implant that monitors the activity of different parts of the brain at the same time, from the surface to deep structures.
Photoreceptor precursor cells (red) are shown with extended axons toward bipolar cells.

Audacious projects develop imaging technology to aid eye tissue regeneration

As regenerative therapies for blinding diseases move closer to clinical trials, the NEI's functional imaging consortium is pioneering noninvasive technologies to monitor the function of the retina’s neurons and their connections to the brain.
Doctor examines patient's eye using slit lamp

Citicoline protects against glaucoma without reducing fluid pressure in eye

A new study showed that ingesting the compound citicoline restored optic nerve (neural) signals between the brain and eye to near-normal levels in the study rats.