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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Slice of OCT image hovers over 3D segmentation of retinal cells

AI Spots Individual Neurons in the Eye Better than Human Experts

A new combination of optical coherence tomography (OCT), adaptive optics and deep neural networks should enable better diagnosis and monitoring for neuron-damaging eye and brain diseases like glaucoma.
city street at night as seen by a person with normal vision

A new theory for what’s happening in the brain when something looks familiar

University of Pennsylvania researchers propose a new theory for how the brain understands the level of activation expected from a sensory input and corrects for it, leaving behind the signal for familiarity.

Neural Implant Monitors Multiple Brain Areas at Once, Provides New Neuroscience Insights

Researchers at UCSD have developed a neural implant that monitors the activity of different parts of the brain at the same time, from the surface to deep structures.
Photoreceptor precursor cells (red) are shown with extended axons toward bipolar cells.

Audacious projects develop imaging technology to aid eye tissue regeneration

As regenerative therapies for blinding diseases move closer to clinical trials, the NEI's functional imaging consortium is pioneering noninvasive technologies to monitor the function of the retina’s neurons and their connections to the brain.
Doctor examines patient's eye using slit lamp

Citicoline protects against glaucoma without reducing fluid pressure in eye

A new study showed that ingesting the compound citicoline restored optic nerve (neural) signals between the brain and eye to near-normal levels in the study rats.

Gene therapy shows promise in treating rare eye disease in mice

A gene therapy protects eye cells in mice with a rare disorder that causes vision loss, especially when used in combination with other gene therapies, shows a study published in eLife.

University of Maryland School of Medicine study identifies new mechanism that may cause blindness in older adults

Using laboratory-grown roundworms as well as human and mouse eye tissue, researchers have identified a new potential mechanism for age-related macular degeneration—the leading cause of blindness among older adults.

Artificial Neuron Device Could Shrink Energy Use and Size of Neural Network Hardware

Training neural networks to perform tasks, such as recognizing images or navigating self-driving cars, could one day require less computing power and hardware thanks to a new artificial neuron device.
Anti-VEGF treatment has greatly improved the prognosis for patients with AMD.

National Eye Institute launches data portal for macular degeneration research

The National Eye Institute (NEI) Data Commons now enables researchers to access data from patients with macular degeneration who participated in the Age-related Eye Disease Study 2 (AREDS2).

Yale team finds dozens of genes that block regeneration of neurons

In a massive screen of 400 mouse genes, Yale School of Medicine researchers have identified 40 genes actively involved in suppression of axon regeneration in central nervous system cells.