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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Sequence of five images, spanning 28 days, shows how regeneration happens in the zebrafish retina.  Rods are shown in green, regenerating cells are shown in red, and all other cells are labeled with blue.  As the rods die, regenerating cells increase and replace the lost rods.

NIH-funded study helps explain how zebrafish recover from blinding injuries

Researchers at Vanderbilt University in Nashville, Tennessee, have discovered that in zebrafish, decreased levels of the neurotransmitter gamma-aminobutyric acid (GABA) cue the retina, the light-sensing tissue in the back of the eye, to produce stem cells
Grantee News

Fighting Blindness: TSRI Scientists Bring a Key Protein into Focus

NEI-funded scientists from The Scripps Research Institute have discovered how a protein called α2δ4 establishes proper vision.
Picture of Aman George in the lab

NIH scientists identify disorder causing blindness, deafness, albinism and fragile bones

Researchers at the National Eye Institute (NEI), part of the National Institutes of Health, have identified the genetic underpinnings of a rare disorder that causes children to be born with deafness, blindness, albinism and fragile bones.
Grantee News

Vitamin B3 Prevents Glaucoma, JAX Researchers Find

In mice genetically predisposed to glaucoma, vitamin B3 added to drinking water is effective at preventing the disease.
Photo shows microscopy image of exosomes in green surrounding retinal ganglion cells in yellow and orange.

Stem cell secretions may protect against glaucoma

A new study in rats shows that stem cell secretions, called exosomes, appear to protect cells in the retina, the light-sensitive tissue in the back of the eye.
Two women panelists look at male colleague as he speaks

Reconnecting Eye to Brain

Michael Crair, Yale University, and Carol Mason, Columbia University, have co-authored a report published online today in the Journal of Neuroscience.
Illuminated neuron projection from visual cortex

Visual cortex plays role in plasticity of eye movement reflex

By peering into the eyes of mice and tracking their ocular movements, researchers made an unexpected discovery: the visual cortex – a region of the brain known to process sensory information – plays a key role...
Grantee News

Culprit identified as a major cause of vision loss

Researchers at Washington University School of Medicine in St. Louis have identified a pathway involved in harming rods and cones and have found a way to halt that damage.
Regenerating mouse retinal ganglion cell axons (magenta and green) extending from site of optic nerve injury (left). Photo courtesy of Andrew D. Huberman.

Use it or Lose it: Visual Activity Regenerates Neural Connections Between Eye and Brain

A study in mice funded by the National Institutes of Health (NIH) shows for the first time that high-contrast visual stimulation can help damaged retinal neurons regrow optic nerve fibers, otherwise known as retinal ganglion cell axons.
Grantee News

Pain medicine helps preserve vision in model of inherited retinal degeneration

A pain medicine that potently activates a receptor vital to a healthy retina appears to help preserve vision in an animal model of severe retinal degeneration, NEI-funded scientists at Medical College of Georgia at Augusta University report.