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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Two women panelists look at male colleague as he speaks

Reconnecting Eye to Brain

Michael Crair, Yale University, and Carol Mason, Columbia University, have co-authored a report published online today in the Journal of Neuroscience.
Illuminated neuron projection from visual cortex

Visual cortex plays role in plasticity of eye movement reflex

By peering into the eyes of mice and tracking their ocular movements, researchers made an unexpected discovery: the visual cortex – a region of the brain known to process sensory information – plays a key role...
Grantee News

Culprit identified as a major cause of vision loss

Researchers at Washington University School of Medicine in St. Louis have identified a pathway involved in harming rods and cones and have found a way to halt that damage.
Regenerating mouse retinal ganglion cell axons (magenta and green) extending from site of optic nerve injury (left). Photo courtesy of Andrew D. Huberman.

Use it or Lose it: Visual Activity Regenerates Neural Connections Between Eye and Brain

A study in mice funded by the National Institutes of Health (NIH) shows for the first time that high-contrast visual stimulation can help damaged retinal neurons regrow optic nerve fibers, otherwise known as retinal ganglion cell axons.
Grantee News

Pain medicine helps preserve vision in model of inherited retinal degeneration

A pain medicine that potently activates a receptor vital to a healthy retina appears to help preserve vision in an animal model of severe retinal degeneration, NEI-funded scientists at Medical College of Georgia at Augusta University report.
Rods and Cones image

NIH Vision Scientists Test Theory of How Rods in our Retina Originated

Retinas from our earliest vertebrate ancestors had cone-like photoreceptors, presumably allowing them to see in daylight, but little ability to see at night.
Grantee News

Scientists reveal new target for anti-lymphangiogenesis drugs

A new study funded in part by NEI and published in Nature Communications reveals a mechanism involved in the regulation of a process called lymphangiogenesis, specifically in corneal transplants and infectious eye disease.
Grantee News

Neuronal Feedback Could Change What We "See"

The brain reacting to feedback between neurons in different parts of the visual system could explain the mechanism behind optical illusions.
Grantee News

Nerve injury appears to be root of diabetes-related vision loss

Diabetes-related vision loss most often is blamed on blood vessel damage in and around the retina, but new research indicates that much of that vision loss may result from nerve cell injury that occurs long before any blood vessels are damaged.
Grantee News

Before Retinal Cells Die, They Regenerate, Penn Vet Blindness Study Finds

Researchers at the University of Pennsylvania showed that in a form of canine blindness retinal cells continue to differentiate for a period of time early in a dog’s life before overwhelming cell death caused the retina to degenerate.