NEI Research News

Researchers at the National Eye Institute (NEI) have shown for the first time how cells across different tissue layers in the eye are affected in people with choroideremia, a rare genetic disorder that leads to blindness.

Researchers from the National Eye Institute (NEI) have developed a gene therapy that rescues cilia defects in retinal cells affected by a type of Leber congenital amaurosis (LCA), a disease that causes blindness in early childhood.

The patient received the therapy as part of a clinical trial that is the first in the United States to use replacement tissues from patient-derived induced pluripotent stem cells.

Three scientific teams that developed physiologically competent retinal organoid systems have won the final phase of the 3D Retinal Organoid Challenge (3D ROC).

The director of the NEI Division of Extramural Science Programs (DESP), passed away on July 30 following a boating accident.

Using a new imaging technique, researchers from the National Eye Institute have determined that retinal lesions from vitelliform macular dystrophy (VMD) vary by gene mutation.

Loss of the protein pigment epithelium-derived factor (PEDF), which protects retinal support cells, may drive age-related changes in the retina, according to a new study in mice from the National Eye Institute.

Clinical trial results from the DRCR Retina Network suggest that a specific step strategy gives results similar to starting off with the higher-priced drug.

The eye’s light-sensing retina taps different circuits depending on whether it is generating image-forming vision or carrying out a non-vision function such as regulating pupil size or sleep/wake cycles, according to a new mouse study.

Did you know the sun's ultraviolet (UV) rays can also damage the eyes? Here are some common questions and answers about UV light and how to protect your eyes from the sun.