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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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126 items
Grantee News

Success of gene therapy for a form of inherited blindness depends on timing

Using a canine model of the vision disorder Leber congenital amaurosis, Penn researchers found that photoreceptor cells continue to deteriorate after treatment if it is given too late.
Grantee News

A Road Map to Stem Cell Development

Johns Hopkins Medicine researchers report they have created a method of mapping how the central nervous system develops by tracking the genes expressed in cells.
Grantee News

With Single Gene Insertion, Blind Mice Regain Sight

Researchers at the University of California, Berkeley, find that restoring opsins with gene therapy can make 'blind' cells light-sensitive; potential human treatment within three years.
Grantee News

Therapy Could Improve, Prolong Sight in Those Suffering Vision Loss

A new therapy developed by researchers at the University of California, Berkeley, could help prolong useful vision and delay total blindness for people with retinitis pigmentosa.
Grantee News

New target could help protect vision following optic nerve trauma

Scientists from the Medical College of Georgia at Augusta University have discovered that removing a pro-inflammatory enzyme promotes regeneration after an injury to the optic nerve.
A scanning electron micrograph image shows a polarized RPE monolayer on a biodegradable scaffold. The image is colored to highlight the scaffold in blue, three RPE cells (brown), and the apical processes of cells in RPE monolayer are light green.

NIH researchers rescue photoreceptors, prevent blindness in animal models of retinal degeneration

Using a novel patient-specific stem cell-based therapy, researchers at the National Eye Institute (NEI) prevented blindness in animal models of geographic atrophy, the advanced “dry” form of age-related macular degeneration (AMD)...
Multiphoton images show the outer segments of cone and rod photoreceptor cells in 215-day retinal organoids. Immunostaining shows a marker for cones (green) and rods (red). The “A” view shows optical sections; “B” is a reconstructed three-dimensional view.

NEI Awards Prize for Progress Toward Developing Lab-Made Retinas

The National Eye Institute (NEI) awarded $25,000 to a team led by Wei Liu, Ph.D., Albert Einstein College of Medicine, for demonstrating progress toward the development of a living model of the human retina...
Images show multimodal technique using adaptive optics and angiography to simultaneously see photoreceptors (left), retinal pigment epithelial cells (center), and choriocapillaris in the living human eye.

NIH scientists combine technologies to view the retina in unprecedented detail

By combining two imaging modalities—adaptive optics and angiography—investigators at the National Eye Institute (NEI) can see live neurons, epithelial cells, and blood vessels deep in the eye’s light-sensing retina.
NEI Audacious Goals Initiative for regenerative medicine in vision identity mark

Five research teams will develop new models for eye disease research

The National Eye Institute (NEI), part of the National Institutes of Health, has awarded grants to five multi-disciplinary teams to develop new disease models for a range of eye conditions.
Illustration of icosahedral virus capsid, containing circular AAV vector. Arrows point from green and blue colored regions of the vector to shRNA and rhodopsin protein, respectively.

Researchers find potential new gene therapy for blinding disease

Scientists funded by the National Eye Institute (NEI) report a novel gene therapy that halts vision loss in a canine model of a blinding condition called autosomal dominant retinitis pigmentosa (adRP).