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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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New technique enhances quality control of lab-grown cells for AMD treatment

NEI researchers improved a crucial step in the production of retinal pigment epithelium (RPE), a tissue they grow in the lab from patient blood cells and are testing in a clinical trial as treatment for AMD.

NEI hosts first workshop on brain-based vision disorder

The National Institutes of Health sponsored its first-ever workshop on cerebral visual impairment (CVI), an umbrella term for subnormal vision resulting from brain injury during development.

NEI posts executive summary of workshop on extracellular vesicles

The September 14 workshop brought together multidisciplinary experts in extracellular vesicles – cell-secreted nanoparticles that mediate cell-cell communication.

U.S. - Ireland R&D Partnership hosts workshop

About 50 participants took part in the virtual event, designed to raise awareness of the U.S.- Ireland R&D Partnership Program.

NEI study shows how genes in retina get regulated during development

Researchers at the National Eye Institute have mapped the 3D organization of genetic material of key developmental stages of human retinal formation, using intricate models of a retina grown in the lab.

Story of discovery: NEI-funded research paves way for new dry AMD drugs

This year, the Food and Drug Administration (FDA) approved Syfovre (pegcetacoplan) and Izervay (avacincaptad pegol), the very first drugs for treating geographic atrophy (GA), also known as late-stage “dry” age-related macular degeneration (AMD).
Richard Lee, NEI's Clinical Director, 2023

National Eye Institute selects Dr. Richard Lee as clinical director

The National Eye Institute (NEI) has chosen Richard Lee, M.D., Ph.D., as the institute’s clinical director, overseeing clinical research and serving as clinical policy advisor for NEI.

Standardizing eye imaging data

The NEI and partners have published an editorial on the value of being able to store and share eye imaging data in standard formats.

Signs of glaucoma may be detectable years in advance of disease onset

Research funded by the National Eye Institute suggests that low density of pigment in the macula, the region of the retina required for sharp central vision, is associated with thinning of the retina and may serve as an early warning sign of glaucoma.

Metabolomics: a new approach to understanding glaucoma

NEI Director Michael F. Chiang featured recent research by NEI grantee Louis Pasquale, Mount Sinai, in an NIH Director’s Blog post.