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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Grantee News

How the Retina Marches to the Beat of Its Own Drum

Researchers at Johns Hopkins and the University of Washington report new research that sheds light on how the retina sets its own biological rhythm using a novel light-sensitive pigment, called neuropsin, found in nerve cells at the back of the eye.
The findings suggest that people may be able to lower their risk of AMD by eating a healthy diet, exercising and by not smoking.

Diet, Exercise, Smoking Habits and Genes Interact to Affect AMD Risk

People with a genetic predisposition for age-related macular degeneration (AMD) significantly increased their odds of developing the blinding eye disorder if they had a history of smoking and did not exercise or eat enough fruits and vegetables.
Grantee News

Identified Genetic Interaction Offers Possible New Target for Glaucoma Therapy

Scientists at the University of California, San Diego School of Medicine have elucidated a genetic interaction that may prove key to the development and progression of glaucoma.
Dr. Rachel Bishop and Dr. Allen Eghrari, from the Johns Hopkins University Wilmer Eye Institute, shown here with the advanced imaging technologies being used for the PREVAIL III study in Monrovia, Liberia.

NEI Team in Liberia Investigates Ocular Effects Among Ebola Survivors

Following the 2014 Ebola outbreak in West Africa that took the lives of more than 11,200 people in the region, the National Eye Institute, part of the National Institutes of Health, has deployed a team of clinicians and technical experts to Monrovia...
Object motion and amacrine cells in retina

Circuit in the Eye Relies on Built-In Delay to See Small Moving Objects

When we move our head, the whole visual world moves across our eyes. Yet we can still make out a bee buzzing by or a hawk flying overhead, thanks to unique cells in the eye called object motion sensors.
NIH study raises doubt about any benefits omega-3 and dietary supplements like these may have for cognitive decline. (Photo courtesy of NEI)

NIH Study Shows no Benefit of Omega-3 or Other Nutritional Supplements for Cognitive Decline

While some research suggests that a diet high in omega-3 fatty acids can protect brain health, a large clinical trial by researchers at the National Institutes of Health found that omega-3 supplements did not slow cognitive decline in older persons.
Schematic of microbiota interacting with ocular immune system.

In Uveitis, Bacteria in Gut May Instruct Immune Cells to Attack the Eye

The inflammatory eye disorder autoimmune uveitis occurs when a person’s immune system goes awry, attacking proteins in the eye.
Grantee News

New clues found to vision loss in macular degeneration​​​

Scientists at Washington University School of Medicine in St. Louis have identified a pathway that leads to the formation of atypical blood vessels that can cause blindness in people with age-related macular degeneration.
Mice with AQP0 mutations (top) had disorderly fiber cells compared to mice with healthy AQP0.

Defective Lens Protein Implicated in Cataract Shown Culprit in Presbyopia

Loss or defects of a protein previously shown to play a key a role in cataract, the clouding of the lens that commonly strikes people in their seventies, has now been shown to contribute to presbyopia.
Images of the brain generated by diffusion tensor imaging, a type of MRI. The red highlights show visual pathways in the brain that deteriorate in patients with LCA, but appear to improve with gene therapy to the retina. Credit: Dr. Manzar Ashtari, University of Pennsylvania.

With LCA Gene Therapy, a Rare Glimpse of the Adult Brain Adapting to New Experience

When people lose the ability to see, how do the visual parts of the brain change in response? And if they regain their sight, are the changes reversed?