Read through policies and procedures related to research and funding.
Get details about NIH’s policies for grantees
NIH grantees generally have to comply with a number of specific policies covering topics like animal welfare, intellectual property, research integrity, and more.
Get guidance for addressing rigor and reproducibility in your application
NIH is committed to supporting the best and most rigorous science.
Find out about policy changes and announcements
Grantees must comply with updated policies from NIH.
Grants management policies
Prior Approval Requests
National Institutes of Health (NIH) Policy allows grantees (recipients) a level of discretion when making changes to budgeting or grant-related activities to meet unanticipated needs. Some changes may be made at the recipient’s discretion as long as they are within the limits established by NIH and the National Eye Institute (NEI); others will require written prior approval as defined in the Grants Policy Statement (GPS) and the terms and conditions in the Notice of Award (NoA).
If you’ve already received an award, but there’s been a change in the status or name of the grantee institution, you can submit an online request to update the information.
- If the institution has changed its organizational status or name, consult the Successor-in-Interest (Type 6 Parent Clinical Trial Optional) FOA
To submit a request for changes, use the Application Submission System & Interface for Submission Tracking (ASSIST) website.
Data and safety monitoring for clinical trials
NEI has stringent policies to protect the safety of participants and the integrity of data in clinical trials that NEI conducts or supports. Get details about the boards that monitor data and safety and how to create a plan for your application.
Data monitoring and oversight of complex epidemiological studies
NEI has stringent policies to protect the safety of participants and the integrity of data in epidemiological studies that NEI conducts or supports. Get details about the appropriate monitoring and oversight of complex epidemiological studies supported by the cooperative agreement mechanism.
NEI’s policy for applications with direct costs of $500,000 or more
Researchers who plan to request $500,000 or more in direct costs in any year must get approval from NEI.
NEI’s fiscal operations plan
NEI's fiscal operations plan reflects our priorities for the current fiscal year.