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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Schematic of photoreceptors and bipolar cells in the retina.

Scientists discover gene therapy provides neuroprotection to prevent glaucoma vision loss

A form of gene therapy protects optic nerve cells and preserves vision in mouse models of glaucoma, according to research supported by NIH’s National Eye Institute. The findings suggest a way forward for developing neuroprotective therapies for glaucoma.
Tiarnan Keenan

Patients use device to monitor AMD at home

Tiarnan Keenan, NEI Division of Epidemiology and Clinical Applications, and colleagues found that people with age-related macular degeneration (AMD) can successfully use the Notal Home OCT device to monitor their disease.
bacteria

E.U. - U.S. NIH collaborative symposium and workshop on AMD and the microbiome

NEI and European researchers hosted international investigators on June 18, 2021, to present and discuss recent advances in age-related macular degeneration (AMD) and its relationship to the microbiome.
Cells with red nuclei and long green processes

Scientists unravel the function of a sight-saving growth factor

Researchers at the National Eye Institute (NEI) have determined how certain short protein fragments, called peptides, can protect neuronal cells found in the light-sensing retina layer at the back of the eye.
Eye diagram showing the uvea, optic nerve, retina, sclera, cornea and pupil.

International coalition classifies 25 subtypes of uveitis, an inflammatory eye disease

An international coalition of eye researchers used machine learning to develop classification criteria for 25 of the most common types of uveitis, a collection of over 30 diseases characterized by inflammation inside the eye.
Photoreceptor precursor cells (red) are shown with extended axons toward bipolar cells.

Audacious projects develop imaging technology to aid eye tissue regeneration

As regenerative therapies for blinding diseases move closer to clinical trials, the NEI's functional imaging consortium is pioneering noninvasive technologies to monitor the function of the retina’s neurons and their connections to the brain.
photoreceptors and retinal ganglion cells are shown on a video play button.

An artificial retina engineered from ancient protein heads to space

LambdaVision, the Farmington, Connecticut-based biotech firm that developed the artificial retina, is exploring optimizing production of an artificial retina in space, in a series of missions to the International Space Station.

NEI joins call for standardization of ophthalmic imaging devices

Not all health care providers speak the same language, but the software in their clinical imaging devices can and should.

Preventive treatment reduces diabetic retinopathy complications

Early treatment with anti-VEGF injections slowed diabetic retinopathy in a clinical study from the DRCR Retina Network (DRCR.net). However, two years into the four-year study its effect on vision was similar to standard treatment.
Anti-VEGF treatment has greatly improved the prognosis for patients with AMD.

National Eye Institute launches data portal for macular degeneration research

The National Eye Institute (NEI) Data Commons now enables researchers to access data from patients with macular degeneration who participated in the Age-related Eye Disease Study 2 (AREDS2).

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