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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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U. Minnesota researchers discover potential new pathway to prevent age-related macular degeneration

The team identified small molecules that can reduce the production of proteins linked to age-related macular degeneration.

Discovery in hibernating animals could extend the shelf life of cells and tissues for transplantation  

Research led by scientists at the National Eye Institute and Sun Yat-sen University, Guangzhou, China points to a potential strategy for extending the cold storage shelf life of donor cells and tissues, such as those of the pancreas.
Mouse retinal blood vessels

How neurons build a 3-D vascular structure to keep the retina healthy

Researchers at UC San Francisco have found a new type of neuron that guides the formation of a lattice of blood vessels nourishes cells in the retina.
Schematic of Mouse arrestin-1 gene.

Study suggests high-frequency electrical ‘noise’ results in congenital night blindness

Findings from mouse study indicate how one mutation of rhodopsin may cause congenital stationary night blindness in humans.
microscopic image of a COVID-19 virion

COVID-19 virus could damage vision

Researchers at the University of Missouri School of Medicine have discovered that the virus that causes COVID-19 can breach the blood-retina barrier with potential long-term consequences in the eye.

Are these newly found rare cells a missing link in color perception?

Researchers used an imaging technology called adaptive optics to identify rare cells that could help fill in the gaps in existing theories of color perception.
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AI makes retinal imaging 100 times faster, compared to manual method

Researchers at the National Institutes of Health applied artificial intelligence (AI) to a technique that produces high-resolution images of cells in the eye. They report that with AI, imaging is 100 times faster and improves image contrast 3.5-fold.
Human iPSC-derived retinal pigment epithelium (RPE).

UC Irvine study shows similarities and differences in human and insect vision formation

Researchers have discovered profound similarities and surprising differences between humans and insects in the production of the critical light-absorbing molecule of the retina, 11-cis-retinal, also known as the “visual chromophore.”

Retinal photoreceptors use dual pathways to tell brain ‘I’ve seen the light!’

Neuroscientists at Johns Hopkins Medicine have shown that intrinsically-photosensitive retinal ganglion cells use two different pathways at the same time to transmit electrical “vision” signals to the brain.
Scientist examines scientific images on a screen in a dark room.

Retinal imaging and genetics data used to predict future disease risk

Researchers combined retinal imaging, genetics and big data to estimate how likely a person is to develop eye and systemic diseases in the future.