Optic Nerve Regeneration: Uncovering Molecular Pathways
Sept. 25, 2018
Jeffrey Goldberg, M.D., Ph.D., presented “Optic Nerve Regeneration: Uncovering Molecular Pathways,” Tuesday, Sept. 25, 2018, on the NIH campus. His lecture was part of the NEI Audacious Goals Initiative (AGI) Seminar Series in Neuroregeneration. Goldberg is chairman of ophthalmology and director of the Byers Eye Institute at Stanford University. He leads a project funded by the National Eye Institute AGI to identify genes and proteins in mice that help or hinder the regenerative capacity of retinal ganglion cells. These neurons carry signals from the eye, through the optic nerve, and to the brain. Loss of these cells, due to diseases including glaucoma, causes irreversible vision loss. However, recent advances by Goldberg and others suggest therapeutic regeneration of retinal ganglion cells may be possible. Goldberg summarized his recent AGI work and highlighted recent progress in neuroregeneration of the visual system.