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416 items

Research points to new hope for treatment-resistant AMD

February 26, 2021

The latest research from the John A. Moran Eye Center reveals how an oxidized form of cholesterol can change choroidal endothelial cells into cells that become scars and may wreak havoc in the eyes of age-related macular degeneration (AMD) patients.
Illustration of the front of the eye

International Team Identifies 127 Glaucoma Genes in Largest Study of Its Kind

February 24, 2021

Researchers for the first time analyzed genes in more than 34,000 people with glaucoma across multiple ancestries and found 44 new genetic variants that may lead to new treatment targets.

New therapeutic approach may help treat age-related macular degeneration effectively

February 22, 2021

Scientists have found that RUNX1 inhibition presents a new therapeutic approach in the treatment of age-related macular degeneration (AMD), which is the leading cause of blindness in the elderly worldwide.

Mount Sinai Researchers Uncover a Neural Pathway that is Critical to Correcting Behavioral Errors Relevant to Many Psychiatric Disorders

February 19, 2021

Mount Sinai researchers have identified a neural pathway through which the brain detects errors and guides subsequent behavioral improvement.

A new vision for AAV-delivered gene therapies

February 10, 2021

A broadly applicable AAV genome-coupled immunomodulation strategy helps cloak the AAV virus from unwanted immune responses, and offers important insights into ocular inflammation.

Cold Sores: Here’s How Stress, Illness and Even Sunburn Trigger Flareups

February 10, 2021

Researchers at the UVA School of Medicine have shed light on what causes herpes simplex virus to flare up, explaining how stress, illness and even sunburn can trigger unwanted outbreaks.

New Research Sheds Light on Vision Loss in Batten Disease

February 5, 2021

New research shows how the mutation associated with Batten disease could potentially lead to degeneration of light sensing photoreceptor cells in the retina, and subsequent vision loss.

Breakthrough by Moran Eye Center Scientist, Colleagues Fuels New Line of Disease Research

February 2, 2021

Scientists at the University of Utah have invented a method for synthesizing large enough quantities of very-long-chain polyunsaturated fatty acids (VLC-PUFAs) to evaluate their potential sight-preserving properties.

HIV Drugs May Help Prevent Blinding Macular Degeneration

February 1, 2021

Scientists have identified a group of drugs that may help stop a leading cause of vision loss after making an unexpected discovery that overturns a fundamental belief about DNA.

Researchers use patients’ cells to test gene therapy for rare eye disease

January 28, 2021

Scientists at the National Eye Institute (NEI) have developed a promising gene therapy strategy for a rare disease that causes severe vision loss in childhood.