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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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FDA-approved drug shows promise in lab models for blinding childhood disease 

March 29, 2023

A National Eye Institute-led team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10).
Rods and Cones image

Early study shows cones in retinal degeneration, thought to be dormant, may retain visual function

March 27, 2023

New UCLA research in mice suggests that “dormant” cone photoreceptors in the degenerating retina are not dormant at all, but continue to function, producing responses to light and driving retinal activity for vision.
Nanoparticle. Courtesy of Biorender.

Tiny nanoparticle could have big impact on patients receiving corneal transplants

March 24, 2023

Using nanoparticles to encapsulate eye medication decreased graft rejection while requiring fewer and smaller doses.
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Night vision tests in age-related macular degeneration precisely localize disease mechanisms

March 17, 2023

Researchers at the University of Alabama at Birmingham discovered that night vision tests at a specific location in the retina will be suitable for assessing treatments and preventions for AMD.
Views of a patio from a walking, crawling, or flying perspective, and a collection of scrambled views.

Visually navigating on foot uses unique brain region

March 15, 2023

Using vision to efficiently move through an area by foot uses a unique region of the brain’s cortex, according to a small study funded by the National Eye Institute (NEI).
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AI-based systems can help identify rapidly advancing age-related macular degeneration

March 14, 2023

Researchers supported by the NEI are developing artificial intelligence/machine learning (AI/ML)-based systems that not only screen for AMD but also predict which patients will likely progress to late within two years.
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Researchers discover therapeutic target to aid in glaucoma treatment

March 13, 2023

Indiana University researchers have identified a new therapeutic target that could lead to more effective treatment of glaucoma.
Older woman's right eye

New insights: Eye damage in Alzheimer’s disease patients

March 3, 2023

Cedars-Sinai investigators map changes to the retina that correspond to brain changes in the early stage of Alzheimer's disease, opening a path to earlier diagnosis.
Woman using eyedrops

Eye experts weigh in on artificial tears in midst of infectious outbreak

March 2, 2023

Questions remain about artificial tears linked to an outbreak of Pseudomonas aeruginosa infections involving 68 people in 16 states, including 5 cases of vision loss, as well as lung and urinary tract infections, and one death.
Fundus photograph of age-related macular degeneration showing drusen.

Discovery suggests new way to prevent common causes of vision loss

February 23, 2023

UVA Health scientists have discovered an unknown contributor to harmful blood vessel growth in the eye that could lead to new treatments for blinding macular degeneration and other common causes of vision loss.

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