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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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NIH researchers supercharge ordinary clinical device to get a better look at the back of the eye

Scientists at the National Institutes of Health (NIH) have leveraged artificial intelligence to transform a device designed to see tissues in the back of the eye into one sharp enough to make out individual cells.

NEI launches new funding mechanism: Grants for intramural investigators

A new NEI intramural grant program called “Innovate Together” enables intramural postdoctoral fellows and staff scientists to explore new tools and techniques.
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AI makes retinal imaging 100 times faster, compared to manual method

Researchers at the National Institutes of Health applied artificial intelligence (AI) to a technique that produces high-resolution images of cells in the eye. They report that with AI, imaging is 100 times faster and improves image contrast 3.5-fold.
Andrew Bower

NEI postdoc to use research award to study cellular function with adaptive optics

The K99/R00 provides a runway for postdocs seeking to transition from mentored positions to tenure track positions at academic institutions in the U.S.
Image of an eye with choroideremia, characterized by enlarged RPE cells.

Novel imaging approach reveals important details about rare eye disease choroideremia

Researchers at the National Eye Institute (NEI) have shown for the first time how cells across different tissue layers in the eye are affected in people with choroideremia, a rare genetic disorder that leads to blindness.
Image of retina

High-tech imaging reveals details about rare eye disorder

Using a new imaging technique, researchers from the National Eye Institute have determined that retinal lesions from vitelliform macular dystrophy (VMD) vary by gene mutation.
Rod and cone photoreceptors are shown in greyscale images.

NIH-led team sets new bar in retinal imaging

A team led by scientists at the National Eye Institute (NEI) has noninvasively visualized the light-sensing cells in the back of the eye, known as photoreceptors, in greater detail than ever before.
Yellow, red and purple multi-colored mosaic

Imaging Method Reveals Long-lived Patterns in Cells of the Eye

Cells of the retinal pigment epithelium (RPE) form unique patterns that can be used to track changes in this important layer of tissue in the back of the eye, researchers at the National Eye Institute (NEI) have found.
Images show multimodal technique using adaptive optics and angiography to simultaneously see photoreceptors (left), retinal pigment epithelial cells (center), and choriocapillaris in the living human eye.

NIH scientists combine technologies to view the retina in unprecedented detail

By combining two imaging modalities—adaptive optics and angiography—investigators at the National Eye Institute (NEI) can see live neurons, epithelial cells, and blood vessels deep in the eye’s light-sensing retina.