NEI Research News

National Eye Institute-funded scientists using gene editing corrected a mutation in a mouse model of retinitis pigmentosa, an inherited blinding eye disorder. The gene editing strategy restored production of rhodopsin, and retinal function and structure

A multidisciplinary team led by researchers at the Schepens Eye Research Institute of Mass Eye and Ear has identified a promising new strategy for glaucoma cell replacement therapy.

Members of the National Eye Institute's Audacious Goals Initiative (AGI) published an outline of milestones to reach before commencing clinical trials of regenerative therapies for retinal disease.

The National Eye Institute has published "Stem cell sources and characterization in the development of cell-based products for treating retinal disease: An NEI town hall report."

A multi-institutional effort led by researchers at the UPenn School of Veterinary Medicine is taking steps to develop an effective technique to regenerate photoreceptors cells and restore sight in people with vision disorders.

A new report outlines progress toward the National Eye Institute's Audacious Goals Initiative (AGI), an effort to restore vision through research in regenerative medicine. The report, published in Nature Medicine.

A new study reveals how photoreceptors grown from stem cells might extend biological wires, known as axons, to contact existing neurons.

Researchers from the U. of Wisconsin have shown that a retinal cell type derived from human pluripotent stem cells is capable of the complex process of detecting light and converting that signal to electrical waves.

Inhibiting ceramide accumulation in the retina helps preserve the retina’s structure and function, and improves vision.

As scientists move closer to testing regenerative therapies for eye disease, techniques are needed to monitor transplanted cells as they integrate with host tissues.