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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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38 items
Baranov and colleague talk in the laboratory.

Mass Eye and Ear researchers develop potential glaucoma treatment strategy to guide stem cells to the retina

A multidisciplinary team led by researchers at the Schepens Eye Research Institute of Mass Eye and Ear has identified a promising new strategy for glaucoma cell replacement therapy.

Putting regenerative therapies on the map

Members of the National Eye Institute's Audacious Goals Initiative (AGI) published an outline of milestones to reach before commencing clinical trials of regenerative therapies for retinal disease.

NEI publishes town hall report on cell-based products for treating retinal disease

The National Eye Institute has published "Stem cell sources and characterization in the development of cell-based products for treating retinal disease: An NEI town hall report."
Photoreceptor precursors

Progress toward a stem cell–based therapy for blindness

A multi-institutional effort led by researchers at the UPenn School of Veterinary Medicine is taking steps to develop an effective technique to regenerate photoreceptors cells and restore sight in people with vision disorders.
NEI AGI audacious Goals Initiative for Regenerative Medicine

NEI's regenerative medicine initiative making progress toward its audacious goal

A new report outlines progress toward the National Eye Institute's Audacious Goals Initiative (AGI), an effort to restore vision through research in regenerative medicine. The report, published in Nature Medicine.
Multicolored image of photoreceptors and their long connecting processes, called axons, within a stem cell-derived retinal organoid

U. Wisconsin eye research uncovers how stem cell photoreceptors reach their targets

A new study reveals how photoreceptors grown from stem cells might extend biological wires, known as axons, to contact existing neurons.
Cone photoreceptors from retinal organoids

UW study finds photoreceptor cells from retinal organoids can replicate key function of vision

Researchers from the U. of Wisconsin have shown that a retinal cell type derived from human pluripotent stem cells is capable of the complex process of detecting light and converting that signal to electrical waves.
mouse retina

UCI researchers discover cause, develop pharmacological treatment for reducing retinitis pigmentosa vision loss

Inhibiting ceramide accumulation in the retina helps preserve the retina’s structure and function, and improves vision.
AGI identity mark

Learning how transplanted neurons fit in

As scientists move closer to testing regenerative therapies for eye disease, techniques are needed to monitor transplanted cells as they integrate with host tissues.
Neurons (green) and their supporting astrocytes (red), created in a petri dish from stem cells.

Cell-replacement Therapies for Visual System Disorders

Two translational studies at the Vanderbilt Eye Institute are targeting photoreceptors and retinal ganglion cells (RGCs) to restore vision through regeneration of the retina. The research is funded by the NEI Audacious Goals Initiative.