NEI Research News

More than 20 years after the launch of a landmark clinical trial, follow-up examinations and analyses found that not all patients with elevated eye pressure need pressure-lowering treatment to prevent vision loss from glaucoma.

Children who undergo cataract surgery as infants have a 22% risk of glaucoma 10 years later, whether or not they receive an intraocular lens implant. The findings come from the National Eye Institute (NEI)-funded Infant Aphakic Treatment Study.

The National Eye Institute (NEI) Audacious Goals Initiative (AGI) is exploring the possibility that the natural world holds the keys to restorative therapies that might unlock regenerative powers in humans.

NEI-funded scientists are hacking the zebrafish’s innate regenerative capacity to learn how to treat human disease.

Researchers have shown for the first time that when one optic nerve in the eye is damaged, as in glaucoma, the opposite optic nerve comes to the rescue by sharing its metabolic energy.

New research by scientists at the Lewis Katz School of Medicine Temple University (LKSOM) shows that gains in functional recovery from optic nerve injuries may be possible, thanks to a molecule known as Lin28, which regulates cell growth.

Neuroscientists at the University of South Florida have become the first to definitively prove pressure in the eye is sufficient to cause and explain glaucoma.

Researchers at the University of South Florida have discovered a novel feedback pathway from the brain to the eye that modulates eye pressure – a significant advancement in the effort to diagnose and treat glaucoma.

A recent study, led by researchers at McGill University, offers an important step in unlocking the mystery of Leber hereditary optic neuropathy’s cause.

Scientists from the Medical College of Georgia at Augusta University have discovered that removing a pro-inflammatory enzyme promotes regeneration after an injury to the optic nerve.