NEI Research News

A study from the National Eye Institute (NEI) identified rare genetic variants that could point to one of the general mechanisms driving age-related macular degeneration (AMD), a common cause of vision loss in older adults.

Texas Congressman Pete Sessions visited the NIH March 27 to meet with NEI Director Michael F. Chiang, M.D., and to tour NEI’s Section on Ocular and Stem Cell Translational Research, led by Kapil Bharti, Ph.D.

A National Eye Institute-led team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10).

New UCLA research in mice suggests that “dormant” cone photoreceptors in the degenerating retina are not dormant at all, but continue to function, producing responses to light and driving retinal activity for vision.

Using nanoparticles to encapsulate eye medication decreased graft rejection while requiring fewer and smaller doses.

Researchers at the University of Alabama at Birmingham discovered that night vision tests at a specific location in the retina will be suitable for assessing treatments and preventions for AMD.

Using vision to efficiently move through an area by foot uses a unique region of the brain’s cortex, according to a small study funded by the National Eye Institute (NEI).

Researchers supported by the NEI are developing artificial intelligence/machine learning (AI/ML)-based systems that not only screen for AMD but also predict which patients will likely progress to late within two years.

Indiana University researchers have identified a new therapeutic target that could lead to more effective treatment of glaucoma.

Cedars-Sinai investigators map changes to the retina that correspond to brain changes in the early stage of Alzheimer's disease, opening a path to earlier diagnosis.