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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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485 items
optic nerves

Nerve regrowth in sight

UConn scientists led by Ephraim Trakhtenberg regrew optic nerves in mice through eye injections of fibronectin peptides (pieces of the larger protein).

UC Irvine-co-led study finds DNA damage is key factor in age-related macular degeneration

Study reveals how DNA damage, a hallmark of aging, compromises the retina’s function and accelerates vision loss. Targeting specific retinal cell types could lead to treatments that slow or stop progression.
Eye illustration

ARPA-H announces funding for development of eye transplantation

ARPA-H announced the teams to receive awards from its Transplantation of Human Eye Allografts (THEA) program.

CRISPR gene editing promising for blinding disease retinitis pigmentosa

National Eye Institute-funded scientists using gene editing corrected a mutation in a mouse model of retinitis pigmentosa, an inherited blinding eye disorder. The gene editing strategy restored production of rhodopsin, and retinal function and structure
Zebrafish, imaged via fluorescence confocal microscopy

New model of neuronal circuit provides insight on eye movement

Working with week-old zebrafish larva, researchers at Weill Cornell Medicine and colleagues decoded how the connections formed by a network of neurons in the brainstem guide the fishes’ gaze.

Flagship AI-ready dataset released in type 2 diabetes study

Researchers today are releasing the flagship dataset from an ambitious study of biomarkers and environmental factors that might influence the development of type 2 diabetes, which is associated with a range of eye diseases such as diabetic retinopathy..
Image of retina

Researchers seek new treatment for blinding diseases AMD and Stargardt

Research team has identified advanced preclinical candidates targeting the bisretinoid synthesis pathway, which could help treat macular degeneration and Stargardt disease.
shingles eye

Long-term, low-dose antiviral treatment benefits patients with eye disease and pain from shingles

New research suggests long-term, low-dose antiviral treatment reduces the risk for potentially vision-damaging bouts of shingles-related eye inflammation, infection, and pain.
Many items on a workbench.

‘Visual clutter’ alters information flow in the brain

Too much stuff in the periphery of our vision can make it difficult to identify what we’re seeing. Yale researchers now know how that clutter affects the brain.
Fundus photograph of age-related macular degeneration showing drusen.

New research offers hope for preventing age-related blindness

New research from the University of Rochester provides important insights into the cellular mechanisms behind AMD and offers potential avenues for new treatments.