NEI Research News

Participants in a phase I/II clinical trial of a new enzyme-based treatment for severe dry eye disease experienced reduced signs of disease and discomfort, according to a paper in Translational Vision Science and Technology.

Omega-3 fatty acid supplements taken orally proved no better than placebo at relieving symptoms or signs of dry eye, according to the findings of a well-controlled trial funded by the National Eye Institute (NEI), part of the National Institutes of Health

Results from a large, national clinical trial show that corneal donor tissue can be safely stored for 11 days without negatively impacting the success of transplantation surgery to restore vision in people with diseases of the cornea.

NEI funded researchers at the University of Illinois at Chicago have identified an enzyme present in the cornea that trigger inflammation during–and even after–a herpes virus infection. Their results are published in the journal Cell Reports.

Bugs in your eyes may be a good thing. Resident microbes living on the eye are essential for immune responses that protect the eye from infection, new research shows.

Recent strides toward understanding dry eye are leading to better and longer-lasting therapies for the millions of people in the U.S. who are affected by the condition.

An international study of more than 5,417 people helps pinpoint the genetic risk factors associated with Fuchs endothelial corneal dystrophy, the most common disorder requiring corneal transplantation.

Children who sleep in unventilated rooms with cooking fires are at greater risk for severe trachoma, a leading cause of preventable blindness in developing countries.

Stem cells from the dental pulp of wisdom teeth can be coaxed to turn into cells of the eye’s cornea and could one day be used to repair corneal scarring due to infection or injury.

Ten years after a transplant, a cornea from a 71-year-old donor is likely to remain as healthy as a cornea from a donor half that age, according to the Cornea Donor Study.