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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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63 items

Gene therapy shows promise in treating rare eye disease in mice

A gene therapy protects eye cells in mice with a rare disorder that causes vision loss, especially when used in combination with other gene therapies, shows a study published in eLife.
photoreceptors and retinal ganglion cells are shown on a video play button.

An artificial retina engineered from ancient protein heads to space

LambdaVision, the Farmington, Connecticut-based biotech firm that developed the artificial retina, is exploring optimizing production of an artificial retina in space, in a series of missions to the International Space Station.
City scene at night. Credit: Luca Bravo on Unsplash

How is night vision maintained during retinal disease?

New research from the University of Utah provides insight on how people with retinal degenerative disease can maintain their night vision for a relatively long period of time.
Photo with only the center visible

UB-UAB collaboration stimulates rethinking of a degenerative eye disease

Researchers from the University of Buffalo have found new information about retinitis pigmentosa, a condition that begins in childhood with night blindness and loss of peripheral vision.
Man getting his eyes examined by a doctor using a slit lamp

Retinitis pigmentosa research probes role of the enzyme DHDDS in this genetic disease

Researchers who made a knock-in mouse-model of the genetic disorder retinitis pigmentosa 59, or RP59, found no retinal degeneration or thinning, calling into question the commonly accepted mechanism for RP59.
photoreceptors

Researchers restore sight in mice by turning skin cells into light-sensing eye cells

Researchers have discovered a technique for directly reprogramming skin cells into light-sensing rod photoreceptors used for vision. The lab-made rods enabled blind mice to detect light after the cells were transplanted into the animals’ eyes.
Eye chart for testing vision

Therapy could improve, prolong sight in those suffering vision loss

Millions of Americans are progressively losing their sight as cells in their eyes deteriorate, but a new therapy developed by researchers at the University of California, Berkeley, could help prolong useful vision and delay total blindness.
Model of protein structure with 4 protein chains

UNH Researchers Solve Protein Structure Associated with Inherited Retinal Diseases

Researchers at the University of New Hampshire have reported the first structural model for a key enzyme, and its activating protein, that can play a role in some genetically inherited eye diseases like retinitis pigmentosa and night blindness.
Rhesus macaque monkey

Discovery in monkeys could lead to treatment for blindness causing syndrome

Oregon National Primate Research Center at OHSU reports first-ever nonhuman primate model for Bardet-Biedl Syndrome
Grantee News

Disruption of glucose transport to rods and cones shown to cause vision loss in retinitis pigmentosa

Retinitis pigmentosa (RP) is a common hereditary eye disorder that leads to the gradual deterioration of rod cells causing reduced peripheral vision and night vision. Subsequent loss of cone photoreceptors cause the loss of high-resolution daylight...