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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Blind People Can’t See Color but Understand It the Same Way as Sighted People

Questioning the belief that that people born blind could never truly understand color, a team of cognitive neuroscientists demonstrated that congenitally blind and sighted individuals actually understand it quite similarly.
Scientists in the laboratory

Retinoblastoma resource: Researchers create more accurate research model

Scientists at St. Jude Children’s Research Hospital have created a laboratory model for studying retinoblastoma driven by inherited mutations in the RB1 gene.

University of Oregon researchers develop gene therapy for eye disease

Researchers have developed a new gene therapy that could eventually provide an alternative treatment for Fuchs’ endothelial corneal dystrophy, a genetic eye disease affecting roughly one in 2,000 people globally.
Scientist looking in a microscope

Retina ‘hardwired’ to predict path of moving objects

Neural circuits in the primate retina can generate the information needed to predict the path of a moving object before visual signals even leave the eye, UW Medicine researchers demonstrate in a new paper.
Neurons (green) and their supporting astrocytes (red), created in a petri dish from stem cells.

Cell-replacement Therapies for Visual System Disorders

Two translational studies at the Vanderbilt Eye Institute are targeting photoreceptors and retinal ganglion cells (RGCs) to restore vision through regeneration of the retina. The research is funded by the NEI Audacious Goals Initiative.
OCT image of a retina

New biomarkers may detect early eye changes that can lead to diabetes-related blindness

New biomarkers found in the eyes could unlock the key to helping manage diabetic retinopathy, and perhaps even diabetes, according to new research conducted at the Indiana University School of Optometry.

Brain’s ‘memory center’ needed to recognize image sequences but not single sights

A new MIT study of how a mammalian brain remembers what it sees shows that while individual images are stored in the visual cortex, the ability to recognize a sequence of sights critically depends on guidance from the hippocampus.
Two boys smile at camera. Dark spot in center of image represents vision loss from AMD.

HtrA1 augmentation is potential therapy for age-related macular degeneration

Research from the University of Utah explains why people with genetic variants may develop age-related macular degeneration (AMD) and identifies a potential therapeutic pathway for slowing disease progression.
eye anatomy graphic

Melanoma of the eye: preclinical tests show path toward treatment

Researchers at UAB have discovered a small molecule inhibitor that dampens the potent drivers of uveal melanoma.
neurons

How neurons get past "no"

When looking at a complex landscape, the eye needs to focus in on important details without losing the big picture. Now, a new study by Salk scientists shows how inhibitory neurons play a critical role in this process.z