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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Micro-molded ‘ice cube tray’ scaffold is next step in returning sight to injured retinas

Researchers at the University of Wisconsin have developed a micro-molded scaffolding photoreceptor “patch” designed to be implanted under a damaged or diseased retina.

Treatment not always needed to prevent vision loss in patients with elevated eye pressure

More than 20 years after the launch of a landmark clinical trial, follow-up examinations and analyses found that not all patients with elevated eye pressure need pressure-lowering treatment to prevent vision loss from glaucoma.
Doctor examines patient's eye using slit lamp

Citicoline protects against glaucoma without reducing fluid pressure in eye

A new study showed that ingesting the compound citicoline restored optic nerve (neural) signals between the brain and eye to near-normal levels in the study rats.

Gene therapy shows promise in treating rare eye disease in mice

A gene therapy protects eye cells in mice with a rare disorder that causes vision loss, especially when used in combination with other gene therapies, shows a study published in eLife.

University of Maryland School of Medicine study identifies new mechanism that may cause blindness in older adults

Using laboratory-grown roundworms as well as human and mouse eye tissue, researchers have identified a new potential mechanism for age-related macular degeneration—the leading cause of blindness among older adults.
Artist's rendering of photoreceptor signaling a retinal ganglion cell

Computer model fosters potential improvements to ‘bionic eye’ technology

Researchers at Keck School of Medicine of USC develop signals that could bring color vision and improved clarity to prosthesis for the blind.
Image shows cone cells, labeled in red.

Turning back the clock on a severe vision disorder

Scientists at the University of Pennsylvania School of Veterinary Medicine report findings of a gene therapy to treat a severe form of Leber congenital amaurosis, caused by mutations in the NPHP5 gene.
Retina model shows RPE cells, choroidal neovascularization-like pathology, vascular layer, PEG layer, Bruch's membrane, drusen

First-ever lab model of human eye offers hope for macular degeneration patients

NEI-funded research at the University of Rochester has led to the development of a 3D lab model that mimics the part of the human retina affected in age-related macular degeneration.

Sign-language exposure impacts infants as young as 5 months old

While it isn’t surprising that infants and children love to look at people’s movements and faces, recent research from Rochester Institute of Technology studies exactly where they look when they see someone using sign language.
Grey scale electron microscopy image of human retinal cells.

New genetic links found to rare eye disease, opening the door to better diagnostics and potential treatments

NEI-funded research at Scripps Research Institute has turned up more than a dozen gene variants linked to MacTel, a rare eye disease. The variants are likely causing the condition to develop and worsen for a significant share of patients.