NEI Research News

New research shows how the mutation associated with Batten disease could potentially lead to degeneration of light sensing photoreceptor cells in the retina, and subsequent vision loss.

Scientists at the National Eye Institute (NEI) have developed a promising gene therapy strategy for a rare disease that causes severe vision loss in childhood.

Researchers from Duke University and Cold Spring Harbor Laboratory discovered that chandelier cells are selectively removed from the developing mouse visual cortex even before the animal’s eyes are open.

Researchers from Florida Atlantic University’s Schmidt College of Medicine hope to conquer a major limitation in the ability for scientists to engineer tissues for regenerative therapies for age-related and degenerative diseases.

The National Eye Institute (NEI) Audacious Goals Initiative (AGI) is exploring the possibility that the natural world holds the keys to restorative therapies that might unlock regenerative powers in humans.

NEI-funded scientists are hacking the zebrafish’s innate regenerative capacity to learn how to treat human disease.

Harvard Medical School surgeons at Massachusetts Eye and Ear have replaced the ocular surface of four patients who each experienced chemical burns to one eye.

A National Eye Institute-funded study has identified a type of stem cell called a neural progenitor cell, in a region of the optic nerve, which connects the eye to the brain.

Using human stem cell models, researchers at Indiana University School of Medicine found they could analyze deficits within cells damaged by glaucoma, with the potential to use this information to develop new strategies to slow the disease process.

Researchers have discovered a technique for directly reprogramming skin cells into light-sensing rod photoreceptors used for vision. The lab-made rods enabled blind mice to detect light after the cells were transplanted into the animals’ eyes.