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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Two hat-shaped objects, one pointing towards the viewer (concave) and one away from the viewer (convex)

Scientists uncover how decisions about what we see are relayed back through the brain

Researchers at the National Institutes of Health have discovered that decisions based on visual information is broadcast widely to neurons in the visual system, including to those that are not being used to make the decision.
OCT image of a retina

New biomarkers may detect early eye changes that can lead to diabetes-related blindness

New biomarkers found in the eyes could unlock the key to helping manage diabetic retinopathy, and perhaps even diabetes, according to new research conducted at the Indiana University School of Optometry.

Brain’s ‘memory center’ needed to recognize image sequences but not single sights

A new MIT study of how a mammalian brain remembers what it sees shows that while individual images are stored in the visual cortex, the ability to recognize a sequence of sights critically depends on guidance from the hippocampus.
Musa Kana

NEI Joins Nigeria’s National Eye Centre in Research Partnership

The National Eye Institute has created a U.S.-Africa vision research collaboration with Nigeria’s National Eye Centre (NEC) to study children’s eye health.
Female shown from overhead standing with her eye open receiving OCT scan.

NEI-funded technology promises to broaden access to retinal scanning

A National Eye Institute-funded project at Duke University has yielded a fully automated optical coherence tomography (OCT) device that does not require a trained operator and promises to broaden access to retinal imaging technology.
Schematic of photoreceptors and bipolar cells in the retina.

Scientists discover gene therapy provides neuroprotection to prevent glaucoma vision loss

A form of gene therapy protects optic nerve cells and preserves vision in mouse models of glaucoma, according to research supported by NIH’s National Eye Institute. The findings suggest a way forward for developing neuroprotective therapies for glaucoma.
Two boys smile at camera. Dark spot in center of image represents vision loss from AMD.

HtrA1 augmentation is potential therapy for age-related macular degeneration

Research from the University of Utah explains why people with genetic variants may develop age-related macular degeneration (AMD) and identifies a potential therapeutic pathway for slowing disease progression.
Tiarnan Keenan

Patients use device to monitor AMD at home

Tiarnan Keenan, NEI Division of Epidemiology and Clinical Applications, and colleagues found that people with age-related macular degeneration (AMD) can successfully use the Notal Home OCT device to monitor their disease.
eye anatomy graphic

Melanoma of the eye: preclinical tests show path toward treatment

Researchers at UAB have discovered a small molecule inhibitor that dampens the potent drivers of uveal melanoma.
neurons

How neurons get past "no"

When looking at a complex landscape, the eye needs to focus in on important details without losing the big picture. Now, a new study by Salk scientists shows how inhibitory neurons play a critical role in this process.z