NEI Research News

Researchers for the first time analyzed genes in more than 34,000 people with glaucoma across multiple ancestries and found 44 new genetic variants that may lead to new treatment targets.

New research shows how the mutation associated with Batten disease could potentially lead to degeneration of light sensing photoreceptor cells in the retina, and subsequent vision loss.

Scientists have identified a group of drugs that may help stop a leading cause of vision loss after making an unexpected discovery that overturns a fundamental belief about DNA.

Scientists at the National Eye Institute (NEI) have developed a promising gene therapy strategy for a rare disease that causes severe vision loss in childhood.

Researchers at the University of Illinois Chicago have published a study showing a promising approach to using drug repurposing to treat genetic diseases.

A multi-university team identified a family of enzymes called GCK-IV kinases whose inhibition is robustly neuroprotective, while also permitting axon regeneration.

Scientists reverse age-related vision loss, glaucoma damage in mice.

A new study shows that deleting one of the inhibitors of the RPE65 gene in a mouse model that carries a human disease mutation prevents degeneration of cone photoreceptors that are used for daytime high-resolution color vision.

A new study from University of Connecticut details a method of characterizing every cell in the cornea using an approach known as single-cell RNA sequence analysis to answer questions about the cornea’s healing process.

New York University researchers created a “developmental atlas” of gene expression in neurons, using gene sequencing and machine learning to categorize more than 250,000 neurons in the brains of fruit flies.