NEI Research News

Mouse, human data suggest inflammation tips immune response, which disrupts oil glands.

Scientists have evidence that variants of the same gene that enables us to make connective tissue by crosslinking proteins is associated with unusual glaucoma.

Immune cells called microglia can completely repopulate themselves in the retina after being nearly eliminated, according to a new study in mice from scientists at the National Eye Institute (NEI).

In a major step forward in the battle against macular degeneration, researchers at the University of Virginia School of Medicine have discovered a critical trigger for the damaging inflammation that ultimately robs millions of their sight.

NIH scientists have simplified manufacturing and dosing of a potential drug candidate for the autoimmune eye disease uveitis—a vision-threatening condition that accounts for about 15 percent of blindness in the U.S.

NEI funded researchers at the University of Illinois at Chicago have identified an enzyme present in the cornea that trigger inflammation during–and even after–a herpes virus infection. Their results are published in the journal Cell Reports.

Bugs in your eyes may be a good thing. Resident microbes living on the eye are essential for immune responses that protect the eye from infection, new research shows.

Systemic therapy consisting of corticosteroids and immunosuppressants preserved vision of uveitis patients better – and had fewer adverse outcomes – than a long-lasting corticosteroid intraocular implant, according to a clinical trial funded by NEI.

Four to 12 percent of people undergoing cataract surgery to replace a cloudy lens with a clear artificial one develop posterior capsule opacification (PCO).

The breast cancer drug tamoxifen appears to protect light-sensitive cells in the eye from degeneration, according to a new study in mice.