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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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63 items

Five innovations harness new technologies for people with visual impairment, blindness

During Low Vision Awareness Month, the National Eye Institute (NEI), part of the National Institutes of Health, is highlighting new technologies and tools in the works to help the 4.1 million Americans living with low vision or blindness.
Grantee News

Retinitis Pigmentosa May Be Treated by Reprogramming Sugar Metabolism

NEI-funded researchers at Columbia University Medical Center have shown that vision loss associated with a form of retinitis pigmentosa can be slowed dramatically by reprogramming the metabolism of photoreceptors, or light sensors, in the retina.
Grantee News

Culprit identified as a major cause of vision loss

Researchers at Washington University School of Medicine in St. Louis have identified a pathway involved in harming rods and cones and have found a way to halt that damage.
Grantee News

Pain medicine helps preserve vision in model of inherited retinal degeneration

A pain medicine that potently activates a receptor vital to a healthy retina appears to help preserve vision in an animal model of severe retinal degeneration, NEI-funded scientists at Medical College of Georgia at Augusta University report.
Grantee News

Before Retinal Cells Die, They Regenerate, Penn Vet Blindness Study Finds

Researchers at the University of Pennsylvania showed that in a form of canine blindness retinal cells continue to differentiate for a period of time early in a dog’s life before overwhelming cell death caused the retina to degenerate.
Grantee News

CRISPR Used to Repair Blindness-causing Genetic Defect in Patient-derived Stem Cells

Columbia University Medical Center (CUMC) and University of Iowa scientists have used a new gene-editing technology called CRISPR to repair a genetic mutation responsible for retinitis pigmentosa (RP), an inherited condition.
The researchers developed a technique to study live cells in patches of retina, shown here by confocal microscopy. After 2 hours, the vast majority of the cells are alive (green); only a few cells at the perimeter have died (stained red with a dye).

Retinal Cells Work with Little Reserve Energy; May Explain Vulnerability to Eye Diseases

Our eyes are especially demanding when it comes to energy: Along with our brain, they require a substantial amount of power to keep them functioning and healthy.
Grantee News

Gene Editing Technique Improves Vision in Rats with Inherited Blindness

A new technique that has the potential to treat inherited diseases by removing genetic defects has been shown for the first time to hinder retinitis pigmentosa, a degenerative eye disease with no known cure that can lead to blindness.
Grantee News

USC Eye Institute researchers discover a way to improve image sharpness for blind people with retinal implants

Retinal implants that deliver longer pulses of electrical current may noticeably improve image sharpness for individuals who have lost their sight due to retinitis pigmentosa, according to a new study.
Image of gene therapy preserved vision in a study involving dogs.

Gene Therapy Staves Off Blindness from Retinitis Pigmentosa in Canine Model

Gene therapy preserved vision in a study involving dogs with naturally occurring, late-stage retinitis pigmentosa, according to research funded by the National Eye Institute (NEI), part of the National Institutes of Health.