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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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140 items
Samarendra Mohanty and Subrata Batabyal

Scientists use gene therapy and a novel light-sensing protein to restore vision in mice

A newly developed light-sensing protein called the MCO1 opsin restores vision in blind mice when attached to retina bipolar cells using gene therapy.

UCI-led study reveals significant restoration of retinal and visual function following gene therapy

New generation CRISPR technology lays foundation for therapeutics to treat a wide range of inherited ocular diseases

FAU Researchers receive $1.3 million NIH grant for stem cell research

Researchers from Florida Atlantic University’s Schmidt College of Medicine hope to conquer a major limitation in the ability for scientists to engineer tissues for regenerative therapies for age-related and degenerative diseases.
Scientist viewed through a laboratory shelf filled with bottles

AGI-supported researchers discover gene pathways that regenerate neurons between the eye and the brain

A team of researchers has identified networks of genes that allow neurons to regenerate in animals like zebrafish.
Retina flattened to 4 lobes, stained yellow and blue

LSU Health show nonharmful stress protects against disease in offspring

Researchers funded by the National Eye Institute show in a mammalian model the reprogramming of heritability to promote disease resilience in the next generation.
David Gamm in the laboratory

UW researchers devise approach to treat rare, incurable form of blindness

Scientists at the University of Wisconsin‒Madison have published a proof-of-concept method to correct an inherited form of macular degeneration that causes blindness, and that is currently untreatable.
neurons

Neurons are genetically programmed to have long lives

Researchers reveal a mechanism by which long-term survival of neurons is intrinsically programmed during development.
Computerized image of an eyeball, optic nerve and brain.

Study points to potential new approach to treating neurodegenerative diseases like glaucoma and Alzheimer’s disease

Researchers have shown for the first time that when one optic nerve in the eye is damaged, as in glaucoma, the opposite optic nerve comes to the rescue by sharing its metabolic energy.
Multicolor image of retina in cross-section

Scientists Use Nanoparticle-Delivered Gene Therapy to Inhibit Blinding Eye Disease in Rodents

In experiments in rats and mice, two Johns Hopkins scientists report the successful use of nanoparticles to deliver gene therapy for blinding eye disease.
Photo with only the center visible

UB-UAB collaboration stimulates rethinking of a degenerative eye disease

Researchers from the University of Buffalo have found new information about retinitis pigmentosa, a condition that begins in childhood with night blindness and loss of peripheral vision.