NEI Research News

The protocol gives step-by-step instructions, starting with patient-derived pluripotent stem cells, transitioning them to retinal pigment epithelium (RPE) cells and finally maturing them into RPE tissue.

Researchers from the National Eye Institute (NEI) have developed a gene therapy that rescues cilia defects in retinal cells affected by a type of Leber congenital amaurosis (LCA), a disease that causes blindness in early childhood.

Three scientific teams that developed physiologically competent retinal organoid systems have won the final phase of the 3D Retinal Organoid Challenge (3D ROC).

A multi-institutional effort led by researchers at the UPenn School of Veterinary Medicine is taking steps to develop an effective technique to regenerate photoreceptors cells and restore sight in people with vision disorders.

Using a new imaging technique, researchers from the National Eye Institute have determined that retinal lesions from vitelliform macular dystrophy (VMD) vary by gene mutation.

Loss of the protein pigment epithelium-derived factor (PEDF), which protects retinal support cells, may drive age-related changes in the retina, according to a new study in mice from the National Eye Institute.

Scientists at LSU Health New Orleans Neuroscience Center of Excellence have developed a new, experimental human cell line from retinal pigment epithelial cells.

The eye’s light-sensing retina taps different circuits depending on whether it is generating image-forming vision or carrying out a non-vision function such as regulating pupil size or sleep/wake cycles, according to a new mouse study.

NEI researcher Mitra Farnoodian Tedrick, Ph.D., received a $65,000 grant from the Knights Templar Eye Foundation (KTEF) to identify drugs to treat a rare blinding condition called Stargardt disease.

A new report outlines progress toward the National Eye Institute's Audacious Goals Initiative (AGI), an effort to restore vision through research in regenerative medicine. The report, published in Nature Medicine.