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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Grantee News

Birthday Matters for Wiring-Up the Brain’s Vision Centers

New study suggests that neurons in the developing brains of mice are guided by a simple but elegant birth order rule that allows them to find and form their proper connections.
Retinal pigment epithelium derived from induced pluripotent stem cells. Photo credit: Dr. Kapil Bharti.

Gene profiling technique to accelerate stem cell therapies for eye diseases

Researchers at the National Institutes of Health have developed a technique that will speed up the production of stem-cell derived tissues.
Grantee News

Patient-Specific Stem Cells and Personalized Gene Therapy

Columbia University Medical Center (CUMC) researchers have created a way to develop personalized gene therapies for patients with retinitis pigmentosa (RP), a leading cause of vision loss.
Grantee News

New Compound Treats Both Blindness and Diabetes in Animal Studies

In a new study, a chemical compound designed to precisely target part of a crucial cellular quality-control network provided significant protection, in rats and mice, against degenerative forms of blindness and diabetes.
An occupational therapist at Thomas Jefferson University works with a patient who has low vision. Credit: Thomas Jefferson University.

Rehabilitation helps prevent depression from age-related vision loss

Depression is a common risk for people who have lost their vision from age-related macular degeneration (AMD), but a new study shows that a type of rehabilitation therapy can cut this risk in half.
NICU care providers take photos of a premature baby's retinas in the NEI-funded e-ROP study of telemedicine for retinopathy of prematurity. Photo credit: Children's Hospital of Philadelphia

Telemedicine catches blinding disease in premature babies

Telemedicine is an effective strategy to screen for the potentially blinding disease known as retinopathy of prematurity (ROP), according to a study funded by the National Eye Institute (NEI).
Chichilnisky and colleagues used an electrode array to record activity from retinal ganglion cells (yellow and blue) and feed it back to them, reproducing the cells' responses to visual stimulation. Credit: E.J. Chichilnisky, Stanford.

Making artificial vision look more natural

In laboratory tests, researchers have used electrical stimulation of retinal cells to produce the same patterns of activity that occur when the retina sees a moving object.
Grantee News

Dodging dots helps explain brain circuitry

A neuroscience study provides new insight into the primal brain circuits involved in collision avoidance, and perhaps a more general model of how neurons can participate in networks to process information and act on it.
Individual cilia grow from the basal body of a cell with assistance from distal and subdistal appendages (Credit: Shobi Veleri, Ph.D., National Eye Institute)

NIH study reveals gene critical to the early development of cilia

Researchers at the National Eye Institute (NEI) have described the functions of a gene responsible for anchoring cilia — sensory hair-like extensions present on almost every cell of the body.
A healthy mouse retina (left) and distinctive folds in a mouse retina damaged by autoimmune uveitis (right). Credit: Wang et al. Nature Medicine, April 2014.

Soothing cells, peaceful protein could hold promise for treating autoimmune uveitis

Researchers at the National Eye Institute (NEI) have found a unique cell type that, in tests on mice, can protect against uveitis—a group of inflammatory diseases that affect the eye and can cause vision loss.