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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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NIH Challenge aimed at incentivizing data sharing recognizes Phase 1 winners

Ten teams are being recognized for their proof-of-concept ideas following Phase 1 of the Data Sharing Index (“S-Index”) Challenge, an NIH competition aimed at incentivizing data sharing

NEI funded research sheds new light on immune cell interactions in retina

During most eye infections or injuries, neutrophils, immune cells found in the blood, are usually the first line of defense. However, new research shows retina responds differently than other tissues in the body.

New research uncovers link between cancer pathway and blood-retina barrier function

A National Eye Institute-funded research team at the University of Minnesota Medical School discovered that a cancer signaling pathway has previously unrecognized roles in retina and brain blood vessels.

Eye cells "rewire" themselves when vision begins to fail

A new study funded by the National Eye Institute shows that certain retinal cells can rewire themselves when vision begins to deteriorate in retinitis pigmentosa, a genetic eye disease that leads to progressive blindness.

Strategy to prevent age-related macular degeneration identified

A new National Eye Institute-supported study identifies a possible way to slow or block progression of age-related macular degeneration (AMD), a leading cause of blindness in people over age 50.

NIH researchers identify brain circuits responsible for visual acuity

Researchers at the National Institutes of Health (NIH) have identified which brain circuits are vital for visual acuity and how they are affected by damaged retinal cells.

NEI-funded researchers test new visual prosthesis system to restore vision

Brown University researchers have identified a promising new approach that may help to restore vision in people affected by macular degeneration and other retinal disorders.

Repurposing a high blood pressure drug may prevent vision loss in inherited blinding diseases

New studies in rats suggest the drug reserpine, approved in 1955 for high blood pressure, might treat the blinding disease retinitis pigmentosa. No therapy exists for this rare inherited disease, which starts affecting vision from childhood.
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NEI-funded researchers “push the ENVLPE” with new virus-like particle to fix mutations causing blindness

New CRISPR gene editing approach may also be useful for treating other inherited diseases, such as cystic fibrosis and familial hypercholesterolemia
Retinal organoid

Researchers ‘seq’ and find a way to make pig retinal cells to advance eye treatments

Researchers have developed lab-grown pig retinal organoids to test stem cell replacement therapies for diseases that damage the eye's light-sensing photoreceptors.