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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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EyeDrops_GlaucomaMedicines.

AI used to advance drug delivery system for glaucoma and other chronic diseases

May 24, 2023

Researchers have used artificial intelligence models and machine-learning algorithms to successfully predict which components of amino acids that make up therapeutic proteins are most likely to safely deliver therapeutic drugs to animal eye cells.
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Researchers discover therapeutic target to aid in glaucoma treatment

March 13, 2023

Indiana University researchers have identified a new therapeutic target that could lead to more effective treatment of glaucoma.
Patient wearing brain pressure measuring device over their eyes.

Low brain pressure could be a risk factor for developing glaucoma

February 13, 2023

A recent international clinical study demonstrates that low intracranial pressure correlates with impaired patient vision, especially in the nasal zone.
Two boys smile at camera. The outer portion of the image is darkened, representing vision loss from glaucoma.

New genetic mutation behind childhood glaucoma identified

November 30, 2022

An international team led by Harvard Medical School scientists has discovered a new genetic mutation that may be a root cause of severe cases of childhood glaucoma, a devastating condition that runs in families.
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New UC Irvine-led study shows repeated stress accelerates aging of the eye

November 21, 2022

Researchers say findings reveal potential glaucoma drugs targets.

3D map reveals DNA organization within human retina cells

October 7, 2022

National Eye Institute researchers mapped the organization of human retinal cell chromatin, the fibers that package 3 billion nucleotide-long DNA molecules into compact structures that fit into chromosomes within each cell’s nucleus.
Graph showing that odd ratio for advanced vision loss for African Americans is significantly higher than for non-hispanic whites.

Black patients found six times more likely to have advanced vision loss after glaucoma diagnosis than white patients

July 25, 2022

Black patients have a dramatically higher risk of advanced vision loss after a new diagnosis of primary open angle glaucoma (POAG) when compared to white patients, according to a new study from New York Eye and Ear Infirmary of Mount Sinai (NYEE).
Kathryn Bollinger Sylvia Smith

Protein protects brain cells most impacted by glaucoma

March 3, 2022

Protein sigma 1 receptor, which is known to protect cells from stress, appears key to the function and survival of retinal ganglion cells (RGCs) in culture.
A diagram of the eye with a green arrow showing how fluid normally passes through the space between the iris and the cornea and drains out of the eye back into the bloodstream.

A new treatment for glaucoma?

October 18, 2021

A Northwestern Medicine study in mice has identified new treatment targets for glaucoma, including preventing a severe pediatric form of glaucoma, as well as uncovering a possible new class of therapy for the most common form of glaucoma in adults.
AGI identity mark

Learning how transplanted neurons fit in

October 7, 2021

As scientists move closer to testing regenerative therapies for eye disease, techniques are needed to monitor transplanted cells as they integrate with host tissues.

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