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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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The image on the left is labeled "Normal retina," and shows green rods and red cones. The image on the right is labeled "Retina affected by retinitis pigmentosa," and shows green rods that have broken down.

Researchers engineer in vivo delivery system for prime editing, partially restoring vision in mice

By adapting virus-like particles to carry the machinery for a type of gene editing called prime editing, scientists have corrected disease-causing mutations in animals and increased editing efficiency.
Office-Glaucoma

New research aims to develop novel therapeutic for glaucoma

Researchers at Indiana University School of Medicine are using a novel approach to hopefully develop a new therapy for glaucoma, a complex disease that eventually leads to blindness.

Pioneering study indicates a potential treatment for corneal endothelial disease, reducing the need for corneal transplants

Findings from a pioneering study reveal that administration of the neuropeptide α-melanocyte–stimulating hormone (α-MSH) promotes corneal healing and restores normal eye function.

NEI posts executive summary of workshop on extracellular vesicles

The September 14 workshop brought together multidisciplinary experts in extracellular vesicles – cell-secreted nanoparticles that mediate cell-cell communication.
Baranov and colleague talk in the laboratory.

Mass Eye and Ear researchers develop potential glaucoma treatment strategy to guide stem cells to the retina

A multidisciplinary team led by researchers at the Schepens Eye Research Institute of Mass Eye and Ear has identified a promising new strategy for glaucoma cell replacement therapy.

UConn health researchers find that youthful proteins help nerves regrow

Ribosomal protein genes that are found at low levels in adult nerve cells may be very important to axon regeneration.

Putting regenerative therapies on the map

Members of the National Eye Institute's Audacious Goals Initiative (AGI) published an outline of milestones to reach before commencing clinical trials of regenerative therapies for retinal disease.

New nerve insights could someday help heal certain types of blindness and paralysis

UConn School of Medicine researchers report that a small population of nerve cells exist in everyone that could be coaxed to regrow, potentially restoring sight and movement after injury.

NEI publishes town hall report on cell-based products for treating retinal disease

The National Eye Institute has published "Stem cell sources and characterization in the development of cell-based products for treating retinal disease: An NEI town hall report."
Rods and Cones image

Early study shows cones in retinal degeneration, thought to be dormant, may retain visual function

New UCLA research in mice suggests that “dormant” cone photoreceptors in the degenerating retina are not dormant at all, but continue to function, producing responses to light and driving retinal activity for vision.