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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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54 items
Phoebe Lin, MD, PhD

Pathway to better eye health runs through the gut

December 21, 2021

Ocular inflammation research from OHSU targets gastrointestinal microbes.

Reimagining immunity in the eye

December 8, 2021

In a new study, the researchers show that immune cells respond to the lens, not just following an acute injury in the eye, but also to long-lasting inflammation.
Mouse retina

NIH scientists discover new B cell that tempers autoimmunity

December 2, 2021

Findings in mice point to potential therapies for blinding eye disease uveitis and multiple sclerosis

Small amounts of carbon monoxide may help protect vision in diabetes

November 4, 2021

The Medical College of Georgia scientists have early evidence that HBI-002, a low-dose oral compound, can safely reduce oxidative stress and inflammation in the retina, both early, major contributors to diabetic retinopathy.
Brad Gelfand, Ph.D., in the laboratory

Prozac Pegged as Potential Treatment for a Leading Cause of Blindness

October 21, 2021

An antidepressant best known as Prozac could offer the first treatment for the leading cause of blindness among people over 50, new research from the University of Virginia School of Medicine suggests.

Toxic DNA Buildup May Drive Macular Degeneration

September 30, 2021

Damaging DNA builds up in the eyes of patients with geographic atrophy, an untreatable, poorly understood form of age-related macular degeneration that causes blindness, new research from the University of Virginia School of Medicine reveals.
Eye diagram showing the uvea, optic nerve, retina, sclera, cornea and pupil.

International coalition classifies 25 subtypes of uveitis, an inflammatory eye disease

June 7, 2021

An international coalition of eye researchers used machine learning to develop classification criteria for 25 of the most common types of uveitis, a collection of over 30 diseases characterized by inflammation inside the eye.
Decorative image of eye

Vision researchers at Wayne State discover new therapy to treat eye infections

May 20, 2021

Researchers at the Wayne State University School of Medicine have discovered that a metabolite called itaconate produced during cellular metabolism plays a role in protecting the eye from abnormal inflammation during infection.

University of Maryland School of Medicine study identifies new mechanism that may cause blindness in older adults

April 12, 2021

Using laboratory-grown roundworms as well as human and mouse eye tissue, researchers have identified a new potential mechanism for age-related macular degeneration—the leading cause of blindness among older adults.

Yale team finds dozens of genes that block regeneration of neurons

March 2, 2021

In a massive screen of 400 mouse genes, Yale School of Medicine researchers have identified 40 genes actively involved in suppression of axon regeneration in central nervous system cells.