Source
23 items

New Research Sheds Light on Vision Loss in Batten Disease

February 5, 2021

New research shows how the mutation associated with Batten disease could potentially lead to degeneration of light sensing photoreceptor cells in the retina, and subsequent vision loss.

Study in mice shows genes may be altered through drug repurposing

December 17, 2020

Researchers at the University of Illinois Chicago have published a study showing a promising approach to using drug repurposing to treat genetic diseases.
David Gamm in the laboratory

UW researchers devise approach to treat rare, incurable form of blindness

July 30, 2020

Scientists at the University of Wisconsin‒Madison have published a proof-of-concept method to correct an inherited form of macular degeneration that causes blindness, and that is currently untreatable.
Multicolor image of retina in cross-section

Scientists Use Nanoparticle-Delivered Gene Therapy to Inhibit Blinding Eye Disease in Rodents

July 7, 2020

In experiments in rats and mice, two Johns Hopkins scientists report the successful use of nanoparticles to deliver gene therapy for blinding eye disease.
Microscopy image of lens and zone fibers stained red, blue and green.

New research on Marfan syndrome focuses on eyes

June 12, 2020

New NEI-supported research provides insight into the eye conditions associated with Marfan syndrome, where weakened zonule fibers cause vision problems.
Surface-dwelling fish with an eye, and pale cave fish without eye

Gene Found that Causes Eyes to Wither in Cavefish

June 2, 2020

University of Maryland-led study identified the first gene responsible for eye loss in cavefish, revealing connection to a human vascular disease.
Rhesus macaque monkey

Discovery in monkeys could lead to treatment for blindness causing syndrome

October 25, 2019

Oregon National Primate Research Center at OHSU reports first-ever nonhuman primate model for Bardet-Biedl Syndrome
7 men look at the camera in a group portrait

NEI Researchers Awarded Grants by the Knights Templar Eye Foundation

July 11, 2019

The Knights Templar Eye Foundation has awarded two NEI scientists grants to research inherited retinal degenerations, diseases that can cause blindness in early childhood.
Photos of study participant with pale hair, left, and darker hair, right.

Nitisinone Increases Melanin in People With Albinism

February 20, 2019

A small pilot clinical study at the National Eye Institute (NEI) suggests that the drug nitisinone increases melanin production in some people with oculocutaneous albinism type 1B (OCA-1B), a rare genetic disease that causes pale skin and hair and poor vi
Grantee News

New study offers hope for patients suffering from a rare form of blindness

October 31, 2018

A new form of therapy may halt or even reverse a form of progressive vision loss, spinocerebellar ataxia type 7 (SCA7). This new therapy has the potential to treat neurogenetic diseases effectively and with far fewer side effects than other medications.