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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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UConn health researchers find that youthful proteins help nerves regrow

Ribosomal protein genes that are found at low levels in adult nerve cells may be very important to axon regeneration.

Patients with specific types of lipids may be at higher risk of developing blinding eye disease

Scientists find association between lipid metabolism and glaucoma.

New nerve insights could someday help heal certain types of blindness and paralysis

UConn School of Medicine researchers report that a small population of nerve cells exist in everyone that could be coaxed to regrow, potentially restoring sight and movement after injury.

Researchers discover therapeutic target to aid in glaucoma treatment

Indiana University researchers have identified a new therapeutic target that could lead to more effective treatment of glaucoma.

New UC Irvine-led study shows repeated stress accelerates aging of the eye

Researchers say findings reveal potential glaucoma drugs targets.
Comparison of two retinal images.

Gene therapy for rare eye disease safe but lacks efficacy in early trial

A 28-patient phase 1 gene therapy clinical trial for the degenerative retinal disease Leber hereditary optic neuropathy (LHON) found no significant safety concerns; however, treatment failed to improve or slow vision loss, with even the highest dose.
Neurons (green) and their supporting astrocytes (red), created in a petri dish from stem cells.

Cell-replacement Therapies for Visual System Disorders

Two translational studies at the Vanderbilt Eye Institute are targeting photoreceptors and retinal ganglion cells (RGCs) to restore vision through regeneration of the retina. The research is funded by the NEI Audacious Goals Initiative.
Image of brain cells with "sparks" of red and yellow

Brain tumors caused by normal neuron activity in mice predisposed to such tumors

A study by researchers at Washington University School of Medicine in St. Louis and Stanford University School of Medicine shows that the normal day-to-day activity of neurons can drive the formation and growth of brain tumors.

Treatment not always needed to prevent vision loss in patients with elevated eye pressure

More than 20 years after the launch of a landmark clinical trial, follow-up examinations and analyses found that not all patients with elevated eye pressure need pressure-lowering treatment to prevent vision loss from glaucoma.
Image shows eye globe, optic nerve, lens, cornea, pupil, meshwork, angle, and where fluid forms and exits the front of the eye.

Cataract surgery in infancy increases glaucoma risk

Children who undergo cataract surgery as infants have a 22% risk of glaucoma 10 years later, whether or not they receive an intraocular lens implant. The findings come from the National Eye Institute (NEI)-funded Infant Aphakic Treatment Study.