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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Grey scale electron microscopy image of human retinal cells.

New genetic links found to rare eye disease, opening the door to better diagnostics and potential treatments

NEI-funded research at Scripps Research Institute has turned up more than a dozen gene variants linked to MacTel, a rare eye disease. The variants are likely causing the condition to develop and worsen for a significant share of patients.

Artificial Neuron Device Could Shrink Energy Use and Size of Neural Network Hardware

Training neural networks to perform tasks, such as recognizing images or navigating self-driving cars, could one day require less computing power and hardware thanks to a new artificial neuron device.
Anti-VEGF treatment has greatly improved the prognosis for patients with AMD.

National Eye Institute launches data portal for macular degeneration research

The National Eye Institute (NEI) Data Commons now enables researchers to access data from patients with macular degeneration who participated in the Age-related Eye Disease Study 2 (AREDS2).
Rod and cone photoreceptors are shown in greyscale images.

NIH-led team sets new bar in retinal imaging

A team led by scientists at the National Eye Institute (NEI) has noninvasively visualized the light-sensing cells in the back of the eye, known as photoreceptors, in greater detail than ever before.

Yale team finds dozens of genes that block regeneration of neurons

In a massive screen of 400 mouse genes, Yale School of Medicine researchers have identified 40 genes actively involved in suppression of axon regeneration in central nervous system cells.

Research points to new hope for treatment-resistant AMD

The latest research from the John A. Moran Eye Center reveals how an oxidized form of cholesterol can change choroidal endothelial cells into cells that become scars and may wreak havoc in the eyes of age-related macular degeneration (AMD) patients.
Illustration of the front of the eye

International Team Identifies 127 Glaucoma Genes in Largest Study of Its Kind

Researchers for the first time analyzed genes in more than 34,000 people with glaucoma across multiple ancestries and found 44 new genetic variants that may lead to new treatment targets.

New therapeutic approach may help treat age-related macular degeneration effectively

Scientists have found that RUNX1 inhibition presents a new therapeutic approach in the treatment of age-related macular degeneration (AMD), which is the leading cause of blindness in the elderly worldwide.

Mount Sinai Researchers Uncover a Neural Pathway that is Critical to Correcting Behavioral Errors Relevant to Many Psychiatric Disorders

Mount Sinai researchers have identified a neural pathway through which the brain detects errors and guides subsequent behavioral improvement.

A new vision for AAV-delivered gene therapies

A broadly applicable AAV genome-coupled immunomodulation strategy helps cloak the AAV virus from unwanted immune responses, and offers important insights into ocular inflammation.

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