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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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140 items
Degenerated RPE cells from mice with geographic atrophy are shown at left. Treating the mice with NRTIs protected the RPE cells. Photos courtesy of Jayakrishna Ambati, M.D.

HIV drugs show promise for “dry” AMD

A class of medications long used to curb HIV infection shows promise as a therapy for age-related macular degeneration (AMD), suggest findings from an NIH-funded study.
Grantee News

New research unlocks a mystery of albinism

Newly published research provides the first demonstration of how a genetic mutation associated with a common form of albinism leads to the lack of melanin pigments that characterizes the condition.
Retinal pigment epithelium derived from induced pluripotent stem cells. Photo credit: Dr. Kapil Bharti.

Gene profiling technique to accelerate stem cell therapies for eye diseases

Researchers at the National Institutes of Health have developed a technique that will speed up the production of stem-cell derived tissues.
Grantee News

Patient-Specific Stem Cells and Personalized Gene Therapy

Columbia University Medical Center (CUMC) researchers have created a way to develop personalized gene therapies for patients with retinitis pigmentosa (RP), a leading cause of vision loss.
Individual cilia grow from the basal body of a cell with assistance from distal and subdistal appendages (Credit: Shobi Veleri, Ph.D., National Eye Institute)

NIH study reveals gene critical to the early development of cilia

Researchers at the National Eye Institute (NEI) have described the functions of a gene responsible for anchoring cilia — sensory hair-like extensions present on almost every cell of the body.
Cross section of retina and optic nerve

Glaucoma: The 'silent thief' begins to tell its secrets

Glaucoma is sometimes called the “silent thief of sight” because it slowly damages the eyes and can cause irreparable harm before there is any vision loss.
Two boys smile at camera. Dark spot in center of image represents vision loss from AMD.

Three studies point to same risk gene for age-related macular degeneration

Three studies reported in Nature Genetics have converged on the same gene as a rare, but powerful risk factor for age-related macular degeneration (AMD), a common cause of vision loss in older people.
close up of proteins

Versatile proteins could be new target for Alzheimer's drugs

A class of proteins that controls visual system development in the young brain also appears to affect vulnerability to Alzheimer’s disease in the aging brain.
National Eye Institute logo.

Glaucoma-linked gene may help insulate optic nerve

Researchers are making progress toward understanding how some cases of glaucoma begin.

Researchers get close-up view of water pores needed in the eye's lens

Researchers have achieved dynamic, atomic-scale views of a protein needed to maintain the transparency of the lens in the human eye.