NEI Research News

Researchers at Louisiana State University have identified a new mechanism that protects against the excessive oxidative stress that precedes the development of neurodegenerative diseases of the brain and eye.

In a comparative analysis across animals of the many cell types in the retina, researchers concluded that most cell types have an ancient evolutionary history.

In a set of 10 papers in Nature, a network of researchers unveiled an atlas cataloging the location and type of every cell in the adult mouse brain.

Researchers at the National Eye Institute have mapped the 3D organization of genetic material of key developmental stages of human retinal formation, using intricate models of a retina grown in the lab.

This year, the Food and Drug Administration (FDA) approved Syfovre (pegcetacoplan) and Izervay (avacincaptad pegol), the very first drugs for treating geographic atrophy (GA), also known as late-stage “dry” age-related macular degeneration (AMD).

Wilmer Eye Institute researchers at Johns Hopkins Medicine have found how oxidative stress and the protein HIF-1 contributes to what kind of age-related macular degeneration (AMD) a patient could develop.

The National Eye Institute (NEI) has chosen Richard Lee, M.D., Ph.D., as the institute’s clinical director, overseeing clinical research and serving as clinical policy advisor for NEI.

The NEI and partners have published an editorial on the value of being able to store and share eye imaging data in standard formats.

Research funded by the National Eye Institute suggests that low density of pigment in the macula, the region of the retina required for sharp central vision, is associated with thinning of the retina and may serve as an early warning sign of glaucoma.

Using atomic force microscopy, researchers at Doheny Eye Institute, an affiliate of University of California Los Angeles, discovered retinal capillary stiffening in diabetic mice that is causally linked to the development of retinopathy