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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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231 items
Eye

Helping the retina regenerate

A new report gives recommendations for regenerating retinal ganglion cells (RGCs), crucial neurons in the back of the eye that carry visual information to the brain.
Image of a mouse retina

NIH scientists deploy CRISPR to preserve photoreceptors in mice

Silencing a gene called Nrl in mice prevents the loss of cells from degenerative diseases of the retina, according to a new study. The findings could lead to novel therapies for preventing vision loss from human diseases such as retinitis pigmentosa.
Xu Wang with Wai Wong in lab

Breast cancer drug dampens immune response, protecting light-sensing cells of the eye

The breast cancer drug tamoxifen appears to protect light-sensitive cells in the eye from degeneration, according to a new study in mice.
Sequence of five images, spanning 28 days, shows how regeneration happens in the zebrafish retina.  Rods are shown in green, regenerating cells are shown in red, and all other cells are labeled with blue.  As the rods die, regenerating cells increase and replace the lost rods.

NIH-funded study helps explain how zebrafish recover from blinding injuries

Researchers at Vanderbilt University in Nashville, Tennessee, have discovered that in zebrafish, decreased levels of the neurotransmitter gamma-aminobutyric acid (GABA) cue the retina, the light-sensing tissue in the back of the eye, to produce stem cells
Grantee News

Fighting Blindness: TSRI Scientists Bring a Key Protein into Focus

NEI-funded scientists from The Scripps Research Institute have discovered how a protein called α2δ4 establishes proper vision.
Grantee News

New Method to Detect Ultrasound with Light

A tiny, transparent device that can fit into a contact lens has a bright future, potentially helping a range of scientific endeavors from biomedicine to geology.
Photo shows microscopy image of exosomes in green surrounding retinal ganglion cells in yellow and orange.

Stem cell secretions may protect against glaucoma

A new study in rats shows that stem cell secretions, called exosomes, appear to protect cells in the retina, the light-sensitive tissue in the back of the eye.
Doctor giving eye exam

Woman who lost vision to diabetes shares experience to raise awareness

It was Labor Day 2015 when Rosetta Ivey-Foster, a 67-year-old retired bank clerk, learned first-hand how quickly diabetes can deteriorate vision.
Grantee News

Culprit identified as a major cause of vision loss

Researchers at Washington University School of Medicine in St. Louis have identified a pathway involved in harming rods and cones and have found a way to halt that damage.
Artist’s rendering of neural activity in the retina. Light that enters the eye activates rod and cone photoreceptors, which then activates retinal ganglion cells. A signal travels to the brain via the retinal ganglion cell axons. Photo credit: National Eye Institute

Six teams seek to identify biological factors that influence neural regeneration

The National Institutes of Health will fund six projects to identify biological factors that affect neural regeneration in the retina.