NEI Research News | National Eye Institute

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125 items

Night vision tests in age-related macular degeneration precisely localize disease mechanisms

March 17, 2023

Researchers at the University of Alabama at Birmingham discovered that night vision tests at a specific location in the retina will be suitable for assessing treatments and preventions for AMD.

Researchers discover therapeutic target to aid in glaucoma treatment

March 13, 2023

Indiana University researchers have identified a new therapeutic target that could lead to more effective treatment of glaucoma.

A person with diabetes checks their blood sugar

Researchers unravel why episodes of low blood sugar worsen eye disease in people with diabetes

January 26, 2023

Researchers at Johns Hopkins Medicine say they have linked transient low blood sugar levels that occur in people with diabetes with a molecular pathway that is turned on in oxygen-starved cells in the eye.

Animation of abnormal blood vessels bleeding into the center of the eye due to proliferative diabetic retinopathy. Photo credit: National Eye Institute. Watch video.

Type 1 diabetes: Maintaining the enzyme ACE2 in the gut prevents diabetic blindness

January 13, 2023

Study from University of Alabama at Birmingham suggests that a leaky small intestine that weakens the barrier between gut bacteria and the blood system may drive diabetic retinopathy.

3D illustration of nanoparticle inside an eye

Nanotechnology may improve gene therapy for blindness

January 11, 2023

Using nanotechnology that enabled mRNA-based COVID-19 vaccines, a new approach to gene therapy may improve how physicians treat inherited forms of blindness.

Microscopy image of red fluorescent retinal neurons

Lab-grown retinal eye cells make successful connections, open door for clinical trials to treat blindness

January 4, 2023

Retinal cells grown from stem cells can reach out and connect with neighbors, according to a new study, completing a “handshake” that may show the cells are ready for trials in humans with degenerative eye disorders.

NIH researchers use 3D bioprinting to create eye tissue

December 22, 2022

Scientists used patient stem cells and 3D bioprinting to produce eye tissue that will advance understanding of the mechanisms of blinding diseases.

Two boys smile at camera. The outer portion of the image is darkened, representing vision loss from glaucoma.

New genetic mutation behind childhood glaucoma identified

November 30, 2022

An international team led by Harvard Medical School scientists has discovered a new genetic mutation that may be a root cause of severe cases of childhood glaucoma, a devastating condition that runs in families.

NEI researchers home in on a new cause of Stargardt disease

October 27, 2022

Using a new stem-cell based model made from skin cells, scientists found the first direct evidence that Stargardt-related ABCA4 gene mutations affect a layer of cells in the eye called the retinal pigment epithelium (RPE).