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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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NEI researchers home in on a new cause of Stargardt disease

October 27, 2022

Using a new stem-cell based model made from skin cells, scientists found the first direct evidence that Stargardt-related ABCA4 gene mutations affect a layer of cells in the eye called the retinal pigment epithelium (RPE).
Fundus photo showing large white patches

Researchers discover new molecular driver of retinoblastoma

September 30, 2022

Study from UT Southwestern Medical Center could lead to new treatments for deadly childhood eye cancer.
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Tuncay first to complete NEI international fellowship in ocular genetics

September 26, 2022

Fulya Yaylacıoğlu Tuncay, M.D., Ph.D., said she gained crucial experience in translational medicine as the first participant in an ocular genetics fellowship program sponsored by NEI and the International Council of Ophthalmology.
Image of an eye with choroideremia, characterized by enlarged RPE cells.

Novel imaging approach reveals important details about rare eye disease choroideremia

September 13, 2022

Researchers at the National Eye Institute (NEI) have shown for the first time how cells across different tissue layers in the eye are affected in people with choroideremia, a rare genetic disorder that leads to blindness.
Retinal organoid with green photoreceptor outer segments.

NIH researchers develop gene therapy for rare ciliopathy

September 8, 2022

Researchers from the National Eye Institute (NEI) have developed a gene therapy that rescues cilia defects in retinal cells affected by a type of Leber congenital amaurosis (LCA), a disease that causes blindness in early childhood.
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First U.S. patient receives autologous stem cell therapy to treat dry AMD

August 31, 2022

The patient received the therapy as part of a clinical trial that is the first in the United States to use replacement tissues from patient-derived induced pluripotent stem cells.
Fluorencent microscope image of retinal organoid colored in red, blue and green

Three teams win NIH’s 3D Retinal Organoid Challenge

August 31, 2022

Three scientific teams that developed physiologically competent retinal organoid systems have won the final phase of the 3D Retinal Organoid Challenge (3D ROC).
Image of retina

High-tech imaging reveals details about rare eye disorder

July 28, 2022

Using a new imaging technique, researchers from the National Eye Institute have determined that retinal lesions from vitelliform macular dystrophy (VMD) vary by gene mutation.
NEI scientists Mitra Farnoodian Tedrick and Kapil Bharti with KTEF Commanders

Knights Templar Eye Foundation funds NEI scientist’s search for therapies to treat blinding eye disease

July 5, 2022

NEI researcher Mitra Farnoodian Tedrick, Ph.D., received a $65,000 grant from the Knights Templar Eye Foundation (KTEF) to identify drugs to treat a rare blinding condition called Stargardt disease.
NEI AGI audacious Goals Initiative for Regenerative Medicine

NEI's regenerative medicine initiative making progress toward its audacious goal

July 5, 2022

A new report outlines progress toward the National Eye Institute's Audacious Goals Initiative (AGI), an effort to restore vision through research in regenerative medicine. The report, published in Nature Medicine.

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