46 items

New treatment targets found for blinding retinal disease

August 10, 2020

When the eye isn’t getting enough oxygen in the face of common conditions like premature birth or diabetes, it can result in blindness. Scientists have identified new points where they may be able to enable recovery.

Combating drug resistance in age-related macular degeneration

July 16, 2020

Researchers have discovered a strategy that can potentially address a major challenge to the current treatment for choroidal neovascularization (CNV), an aggressive form of age-related macular degeneration.

Machine learning helps grow artificial organs

July 7, 2020

Researchers have developed a neural network capable of recognizing retinal tissues during the process of their differentiation in a dish.

Scientists Use Nanoparticle-Delivered Gene Therapy to Inhibit Blinding Eye Disease in Rodents

July 7, 2020

In experiments in rats and mice, two Johns Hopkins scientists report the successful use of nanoparticles to deliver gene therapy for blinding eye disease.

Exercise Can Slow or Prevent Vision Loss, Study Finds

June 30, 2020

Exercise can slow or prevent the development of macular degeneration and may benefit other common causes of vision loss, such as glaucoma and diabetic retinopathy, new research from the University of Virginia suggests.

Pace of eye disease over two years predicts long-term outcome

May 18, 2020

Progression along an age-related macular degeneration (AMD) severity scale over two years predicts the likelihood of developing late-stage disease five years later.

New gene therapy delivery system aims for precision

May 4, 2020

In a novel approach to gene therapy, scientists funded by the National Eye Institute (NEI) report using gold nanoparticles and light to target specific cells in mouse retina.

NEI researchers link age-related DNA modifications to susceptibility to eye disease

April 21, 2020

National Eye Institute (NEI) researchers profiling epigenomic changes in light-sensing mouse photoreceptors have a clearer picture of how age-related eye diseases may be linked to age-related changes in the regulation of gene expression.

Researchers restore sight in mice by turning skin cells into light-sensing eye cells

April 15, 2020

Researchers have discovered a technique for directly reprogramming skin cells into light-sensing rod photoreceptors used for vision. The lab-made rods enabled blind mice to detect light after the cells were transplanted into the animals’ eyes.

Diet may help preserve cognitive function

April 14, 2020

According to a recent analysis of data from two major eye disease studies, adherence to the Mediterranean diet – high in vegetables, whole grains, fish, and olive oil – correlates with higher cognitive function.