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90 items

Toxic DNA Buildup May Drive Macular Degeneration

September 30, 2021

Damaging DNA builds up in the eyes of patients with geographic atrophy, an untreatable, poorly understood form of age-related macular degeneration that causes blindness, new research from the University of Virginia School of Medicine reveals.
Two boys smile at camera. Dark spot in center of image represents vision loss from AMD.

AMD: Reading ability crucial indicator of functional loss

September 30, 2021

In geographic atrophy, a late form of age-related macular degeneration (AMD), reading ability is closely related to the altered retinal structure.
Rajendra Apte examining a patient's eye

The latest on AMD

August 5, 2021

Dr. Rajendra Apte answers common questions about age-related macular degeneration.
Female shown from overhead standing with her eye open receiving OCT scan.

NEI-funded technology promises to broaden access to retinal scanning

July 22, 2021

A National Eye Institute-funded project at Duke University has yielded a fully automated optical coherence tomography (OCT) device that does not require a trained operator and promises to broaden access to retinal imaging technology.
Two boys smile at camera. Dark spot in center of image represents vision loss from AMD.

HtrA1 augmentation is potential therapy for age-related macular degeneration

July 19, 2021

Research from the University of Utah explains why people with genetic variants may develop age-related macular degeneration (AMD) and identifies a potential therapeutic pathway for slowing disease progression.
Tiarnan Keenan

Patients use device to monitor AMD at home

July 16, 2021

Tiarnan Keenan, NEI Division of Epidemiology and Clinical Applications, and colleagues found that people with age-related macular degeneration (AMD) can successfully use the Notal Home OCT device to monitor their disease.
Photoreceptor precursor cells (red) are shown with extended axons toward bipolar cells.

Audacious projects develop imaging technology to aid eye tissue regeneration

April 21, 2021

As regenerative therapies for blinding diseases move closer to clinical trials, the NEI's functional imaging consortium is pioneering noninvasive technologies to monitor the function of the retina’s neurons and their connections to the brain.

Micro-molded ‘ice cube tray’ scaffold is next step in returning sight to injured retinas

April 21, 2021

Researchers at the University of Wisconsin have developed a micro-molded scaffolding photoreceptor “patch” designed to be implanted under a damaged or diseased retina.

University of Maryland School of Medicine study identifies new mechanism that may cause blindness in older adults

April 12, 2021

Using laboratory-grown roundworms as well as human and mouse eye tissue, researchers have identified a new potential mechanism for age-related macular degeneration—the leading cause of blindness among older adults.
Retina model shows RPE cells, choroidal neovascularization-like pathology, vascular layer, PEG layer, Bruch's membrane, drusen

First-ever lab model of human eye offers hope for macular degeneration patients

March 30, 2021

NEI-funded research at the University of Rochester has led to the development of a 3D lab model that mimics the part of the human retina affected in age-related macular degeneration.