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58 items

Yale team finds dozens of genes that block regeneration of neurons

March 2, 2021

In a massive screen of 400 mouse genes, Yale School of Medicine researchers have identified 40 genes actively involved in suppression of axon regeneration in central nervous system cells.
Illustration of the front of the eye

International Team Identifies 127 Glaucoma Genes in Largest Study of Its Kind

February 24, 2021

Researchers for the first time analyzed genes in more than 34,000 people with glaucoma across multiple ancestries and found 44 new genetic variants that may lead to new treatment targets.

New Research Sheds Light on Vision Loss in Batten Disease

February 5, 2021

New research shows how the mutation associated with Batten disease could potentially lead to degeneration of light sensing photoreceptor cells in the retina, and subsequent vision loss.

HIV Drugs May Help Prevent Blinding Macular Degeneration

February 1, 2021

Scientists have identified a group of drugs that may help stop a leading cause of vision loss after making an unexpected discovery that overturns a fundamental belief about DNA.

Researchers use patients’ cells to test gene therapy for rare eye disease

January 28, 2021

Scientists at the National Eye Institute (NEI) have developed a promising gene therapy strategy for a rare disease that causes severe vision loss in childhood.

Study in mice shows genes may be altered through drug repurposing

December 17, 2020

Researchers at the University of Illinois Chicago have published a study showing a promising approach to using drug repurposing to treat genetic diseases.

Researchers Discover Clue to How to Protect Neurons and Encourage Their Growth

December 14, 2020

A multi-university team identified a family of enzymes called GCK-IV kinases whose inhibition is robustly neuroprotective, while also permitting axon regeneration.
Axon nerve fibers on a red background

Vision Revision

December 2, 2020

Scientists reverse age-related vision loss, glaucoma damage in mice.

LSU Health New Orleans Discovers Drug Development Target for Retinal Dystrophies

December 1, 2020

A new study shows that deleting one of the inhibitors of the RPE65 gene in a mouse model that carries a human disease mutation prevents degeneration of cone photoreceptors that are used for daytime high-resolution color vision.
diagram of the eye

Unique Schwann Cells: The Eyes Have It

November 20, 2020

A new study from University of Connecticut details a method of characterizing every cell in the cornea using an approach known as single-cell RNA sequence analysis to answer questions about the cornea’s healing process.