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105 items
Scientists in the laboratory

Retinoblastoma resource: Researchers create more accurate research model

August 6, 2021

Scientists at St. Jude Children’s Research Hospital have created a laboratory model for studying retinoblastoma driven by inherited mutations in the RB1 gene.

University of Oregon researchers develop gene therapy for eye disease

August 3, 2021

Researchers have developed a new gene therapy that could eventually provide an alternative treatment for Fuchs’ endothelial corneal dystrophy, a genetic eye disease affecting roughly one in 2,000 people globally.
NIH National Eye Institute logo

NEI Joins Nigeria’s National Eye Centre in Research Partnership

July 23, 2021

The National Eye Institute has created a U.S.-Africa vision research collaboration with Nigeria’s National Eye Centre (NEC) to study children’s eye health.
Two boys smile at camera. Dark spot in center of image represents vision loss from AMD.

HtrA1 augmentation is potential therapy for age-related macular degeneration

July 19, 2021

Research from the University of Utah explains why people with genetic variants may develop age-related macular degeneration (AMD) and identifies a potential therapeutic pathway for slowing disease progression.
A mug of coffee

High caffeine consumption may be associated with increased risk of blinding eye disease

June 7, 2021

Consuming large amounts of daily caffeine may increase the risk of glaucoma more than three-fold for those with a genetic predisposition to higher eye pressure according to an international, multi-center study.
Image of brain cells with "sparks" of red and yellow

Brain tumors caused by normal neuron activity in mice predisposed to such tumors

May 26, 2021

A study by researchers at Washington University School of Medicine in St. Louis and Stanford University School of Medicine shows that the normal day-to-day activity of neurons can drive the formation and growth of brain tumors.

Gene therapy shows promise in treating rare eye disease in mice

April 13, 2021

A gene therapy protects eye cells in mice with a rare disorder that causes vision loss, especially when used in combination with other gene therapies, shows a study published in eLife.
Image shows cone cells, labeled in red.

Turning back the clock on a severe vision disorder

March 31, 2021

Scientists at the University of Pennsylvania School of Veterinary Medicine report findings of a gene therapy to treat a severe form of Leber congenital amaurosis, caused by mutations in the NPHP5 gene.
Grey scale electron microscopy image of human retinal cells.

New genetic links found to rare eye disease, opening the door to better diagnostics and potential treatments

March 25, 2021

NEI-funded research at Scripps Research Institute has turned up more than a dozen gene variants linked to MacTel, a rare eye disease. The variants are likely causing the condition to develop and worsen for a significant share of patients.

Yale team finds dozens of genes that block regeneration of neurons

March 2, 2021

In a massive screen of 400 mouse genes, Yale School of Medicine researchers have identified 40 genes actively involved in suppression of axon regeneration in central nervous system cells.