20 items

Researchers restore sight in mice by turning skin cells into light-sensing eye cells

April 15, 2020

Researchers have discovered a technique for directly reprogramming skin cells into light-sensing rod photoreceptors used for vision. The lab-made rods enabled blind mice to detect light after the cells were transplanted into the animals’ eyes.

Therapy could improve, prolong sight in those suffering vision loss

March 13, 2020

Millions of Americans are progressively losing their sight as cells in their eyes deteriorate, but a new therapy developed by researchers at the University of California, Berkeley, could help prolong useful vision and delay total blindness.

UNH Researchers Solve Protein Structure Associated with Inherited Retinal Diseases

December 23, 2019

Researchers at the University of New Hampshire have reported the first structural model for a key enzyme, and its activating protein, that can play a role in some genetically inherited eye diseases like retinitis pigmentosa and night blindness.

Discovery in monkeys could lead to treatment for blindness causing syndrome

October 25, 2019

Oregon National Primate Research Center at OHSU reports first-ever nonhuman primate model for Bardet-Biedl Syndrome

Disruption of glucose transport to rods and cones shown to cause vision loss in retinitis pigmentosa

July 30, 2019

Retinitis pigmentosa (RP) is a common hereditary eye disorder that leads to the gradual deterioration of rod cells causing reduced peripheral vision and night vision. Subsequent loss of cone photoreceptors cause the loss of high-resolution daylight...

NEI Researchers Awarded Grants by the Knights Templar Eye Foundation

July 11, 2019

The Knights Templar Eye Foundation has awarded two NEI scientists grants to research inherited retinal degenerations, diseases that can cause blindness in early childhood.

Immune System Can Slow Degenerative Eye Disease, NIH-led Mouse Study Shows

June 17, 2019

A new study shows that the complement system, part of the innate immune system, plays a protective role to slow retinal degeneration in a mouse model of retinitis pigmentosa, an inherited eye disease.

Researchers find potential new gene therapy for blinding disease

August 20, 2018

Scientists funded by the National Eye Institute (NEI) report a novel gene therapy that halts vision loss in a canine model of a blinding condition called autosomal dominant retinitis pigmentosa (adRP).

Immune cells in the retina can spontaneously regenerate

March 21, 2018

Immune cells called microglia can completely repopulate themselves in the retina after being nearly eliminated, according to a new study in mice from scientists at the National Eye Institute (NEI).

Breast cancer drug dampens immune response, protecting light-sensing cells of the eye

March 13, 2017

The breast cancer drug tamoxifen appears to protect light-sensitive cells in the eye from degeneration, according to a new study in mice.