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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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41 items
Rod outer segment showing connector

UC Irvine researchers reveal molecular mechanisms of eye disease using cryo-electron tomography

January 4, 2022

Understanding the key structural determinants of a highly specialized membrane in the eye could lead to new treatments.
Mother and her daughter smile for the camera

Genomic Study Revealing Among Diverse Populations with Inherited Retinal Disease

October 19, 2021

International effort identified new and different causative gene variants for a group of diseases that can lead to severe vision loss or blindness.

Gene therapy shows promise in treating rare eye disease in mice

April 13, 2021

A gene therapy protects eye cells in mice with a rare disorder that causes vision loss, especially when used in combination with other gene therapies, shows a study published in eLife.
photoreceptors and retinal ganglion cells are shown on a video playbutton.

An artificial retina engineered from ancient protein heads to space

April 12, 2021

LambdaVision, the Farmington, Connecticut-based biotech firm that developed the artificial retina, is exploring optimizing production of an artificial retina in space, in a series of missions to the International Space Station.
City scene at night. Credit: Luca Bravo on Unsplash

How is night vision maintained during retinal disease?

September 24, 2020

New research from the University of Utah provides insight on how people with retinal degenerative disease can maintain their night vision for a relatively long period of time.
Photo with only the center visible

UB-UAB collaboration stimulates rethinking of a degenerative eye disease

June 25, 2020

Researchers from the University of Buffalo have found new information about retinitis pigmentosa, a condition that begins in childhood with night blindness and loss of peripheral vision.
Man getting his eyes examined by a doctor using a slit lamp

Retinitis pigmentosa research probes role of the enzyme DHDDS in this genetic disease

June 10, 2020

Researchers who made a knock-in mouse-model of the genetic disorder retinitis pigmentosa 59, or RP59, found no retinal degeneration or thinning, calling into question the commonly accepted mechanism for RP59.
photoreceptors

Researchers restore sight in mice by turning skin cells into light-sensing eye cells

April 15, 2020

Researchers have discovered a technique for directly reprogramming skin cells into light-sensing rod photoreceptors used for vision. The lab-made rods enabled blind mice to detect light after the cells were transplanted into the animals’ eyes.
Eye chart for testing vision

Therapy could improve, prolong sight in those suffering vision loss

March 13, 2020

Millions of Americans are progressively losing their sight as cells in their eyes deteriorate, but a new therapy developed by researchers at the University of California, Berkeley, could help prolong useful vision and delay total blindness.
Model of protein structure with 4 protein chains

UNH Researchers Solve Protein Structure Associated with Inherited Retinal Diseases

December 23, 2019

Researchers at the University of New Hampshire have reported the first structural model for a key enzyme, and its activating protein, that can play a role in some genetically inherited eye diseases like retinitis pigmentosa and night blindness.