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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Employee Offers Personal Account of NIH-Supported Clinical Research

July 22, 2022

Dr. David Kosub shares a first-hand experience of participating in the National Ophthalmic Disease Genotyping and Phenotyping Network (eyeGENE).
Multicolored image of photoreceptors and their long connecting processes, called axons, within a stem cell-derived retinal organoid

U. Wisconsin eye research uncovers how stem cell photoreceptors reach their targets

June 15, 2022

A new study reveals how photoreceptors grown from stem cells might extend biological wires, known as axons, to contact existing neurons.
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NEI researchers discover cellular events that precede neurodegenerative eye disease

April 21, 2022

Molecular and cellular changes in rod photoreceptors are detectable in a mouse model of retinal degeneration several days prior to observable morphological changes, according to researchers at the National Eye Institute.
Stained image of retina

Correcting night blindness in dogs

March 22, 2022

University of Pennsylvania researchers have developed a gene therapy that restores dim-light vision in dogs with a congenital form of night blindness, offering hope for treating a similar condition in people.
Green retinal ganglion cell spreads dendrites in all directions.

Antabuse may help revive vision in people with progressive blinding disorders

March 18, 2022

Researchers at the University of California, Berkeley, have found that a drug once widely used to wean alcoholics off of drinking helps to improve sight in mice with retinal degeneration.
mouse retina

UCI researchers discover cause, develop pharmacological treatment for reducing retinitis pigmentosa vision loss

January 26, 2022

Inhibiting ceramide accumulation in the retina helps preserve the retina’s structure and function, and improves vision.
Rod outer segment showing connector

UC Irvine researchers reveal molecular mechanisms of eye disease using cryo-electron tomography

January 4, 2022

Understanding the key structural determinants of a highly specialized membrane in the eye could lead to new treatments.
Mother and her daughter smile for the camera

Genomic Study Revealing Among Diverse Populations with Inherited Retinal Disease

October 19, 2021

International effort identified new and different causative gene variants for a group of diseases that can lead to severe vision loss or blindness.

Gene therapy shows promise in treating rare eye disease in mice

April 13, 2021

A gene therapy protects eye cells in mice with a rare disorder that causes vision loss, especially when used in combination with other gene therapies, shows a study published in eLife.
photoreceptors and retinal ganglion cells are shown on a video playbutton.

An artificial retina engineered from ancient protein heads to space

April 12, 2021

LambdaVision, the Farmington, Connecticut-based biotech firm that developed the artificial retina, is exploring optimizing production of an artificial retina in space, in a series of missions to the International Space Station.

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