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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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939 items

NEI-funded researchers test new visual prosthesis system to restore vision

Brown University researchers have identified a promising new approach that may help to restore vision in people affected by macular degeneration and other retinal disorders.

Repurposing a high blood pressure drug may prevent vision loss in inherited blinding diseases

New studies in rats suggest the drug reserpine, approved in 1955 for high blood pressure, might treat the blinding disease retinitis pigmentosa. No therapy exists for this rare inherited disease, which starts affecting vision from childhood.
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NEI-funded researchers “push the ENVLPE” with new virus-like particle to fix mutations causing blindness

New CRISPR gene editing approach may also be useful for treating other inherited diseases, such as cystic fibrosis and familial hypercholesterolemia

NIH researchers develop eye drops that slow vision loss in animals

Researchers at the National Institutes of Health (NIH) have developed eye drops that extend vision in animal models of a group of inherited diseases that lead to progressive vision loss in humans, known as retinitis pigmentosa.
Man getting eye exam

Glaucoma monitoring lags in low-income and rural areas

Northwestern study finds ‘alarming’ disparities — lack of glaucoma care can lead to blindness.
Retinal organoid

Researchers ‘seq’ and find a way to make pig retinal cells to advance eye treatments

Researchers have developed lab-grown pig retinal organoids to test stem cell replacement therapies for diseases that damage the eye's light-sensing photoreceptors.
eye with herpes stromal keratitis

Wayne State researchers find potential mechanism to protect against infection-induced vision impairment

Herpes stromal keratitis is a debilitating vision condition that occurs in response to a herpes infection in the eye.
Scientist examines Western blots in the laboratory.

Novel stem cell therapy repairs irreversible corneal damage in clinical trial

A clinical trial that tested an experimental stem cell treatment for blinding cornea injuries found the treatment was feasible and safe in 14 patients, and there was a high proportion of complete or partial success.
eye image

Mount Sinai-led research team identifies underlying mechanisms of age-related dysfunction in glands crucial to eye function

A team led by researchers at Mount Sinai has identified in mice a potential therapeutic target for dry eye disease.
mouse

New study uncovers how genes influence retinal aging and brain health

Researchers at the Jackson Laboratories used mice with nine different genetic backgrounds to identify factors influencing eye aging, paving the way for eye-based diagnostics for neurodegenerative diseases

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