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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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231 items

Study confirms long-term benefit of implant for blinding eye disease

A new study spearheaded by investigators at Scripps Research and the National Eye Institute offers compelling evidence that vision loss from macular telangiectasia can be slowed with a neuroprotective surgical implant.

NEI funded research sheds new light on immune cell interactions in retina

During most eye infections or injuries, neutrophils, immune cells found in the blood, are usually the first line of defense. However, new research shows retina responds differently than other tissues in the body.

New research uncovers link between cancer pathway and blood-retina barrier function

A National Eye Institute-funded research team at the University of Minnesota Medical School discovered that a cancer signaling pathway has previously unrecognized roles in retina and brain blood vessels.

NIH researchers identify brain circuits responsible for visual acuity

Researchers at the National Institutes of Health (NIH) have identified which brain circuits are vital for visual acuity and how they are affected by damaged retinal cells.

NIH researchers supercharge ordinary clinical device to get a better look at the back of the eye

Scientists at the National Institutes of Health (NIH) have leveraged artificial intelligence to transform a device designed to see tissues in the back of the eye into one sharp enough to make out individual cells.

NEI-funded researchers test new visual prosthesis system to restore vision

Brown University researchers have identified a promising new approach that may help to restore vision in people affected by macular degeneration and other retinal disorders.
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NEI-funded researchers “push the ENVLPE” with new virus-like particle to fix mutations causing blindness

New CRISPR gene editing approach may also be useful for treating other inherited diseases, such as cystic fibrosis and familial hypercholesterolemia
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New study uncovers how genes influence retinal aging and brain health

Researchers at the Jackson Laboratories used mice with nine different genetic backgrounds to identify factors influencing eye aging, paving the way for eye-based diagnostics for neurodegenerative diseases

NEI study: New take on old marker of cell death

New findings from a National Eye Institute-led study add a twist on how a widely used cell death marker, annexin-V, can be interpreted in the lab and the clinic for tracking retinal cell death in eye diseases such as glaucoma.

CRISPR gene editing promising for blinding disease retinitis pigmentosa

National Eye Institute-funded scientists using gene editing corrected a mutation in a mouse model of retinitis pigmentosa, an inherited blinding eye disorder. The gene editing strategy restored production of rhodopsin, and retinal function and structure