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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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152 items
mouse retina

UCI researchers discover cause, develop pharmacological treatment for reducing retinitis pigmentosa vision loss

January 26, 2022

Inhibiting ceramide accumulation in the retina helps preserve the retina’s structure and function, and improves vision.
Image of a heart superimposed over a retinal image

AI can identify heart disease from an eye scan

January 25, 2022

Scientists have developed an artificial intelligence system that can analyze eye scans taken during a routine visit to an optician or eye clinic and identify patients at a high risk of a heart attack.
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NIH study classifies vision loss and retinal changes in Stargardt disease

January 25, 2022

National Eye Institute researchers developed and validated an artificial-intelligence-based method to evaluate patients with Stargardt, an eye disease that can lead to childhood vision loss.
Jackie Norrie and Victoria Honnell

Modular super-enhancer controls retinal development

January 11, 2022

Scientists at St. Jude Children’s Research Hospital identified distinct functions for regions of a super-enhancer that controls gene expression during retina formation, calling it a ‘modular’ super-enhancer.
Group of cells tinted purple in the middle and pink at the edges representing a human induced stem cell colony from a patient with albinism.

NIH researchers develop first stem cell model of albinism to study related eye conditions

January 11, 2022

Researchers at the National Eye Institute (NEI) have developed the first patient-derived stem cell model for studying eye conditions related to oculocutaneous albinism (OCA).
Rod outer segment showing connector

UC Irvine researchers reveal molecular mechanisms of eye disease using cryo-electron tomography

January 4, 2022

Understanding the key structural determinants of a highly specialized membrane in the eye could lead to new treatments.
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NIH researchers identify potential AMD drugs with stem-cell based research tool

December 15, 2021

Using a stem-cell-derived model, researchers have identified two drug candidates that may slow dry age-related macular degeneration (AMD), a leading cause of blindness for which no treatment exists.
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NIH study traces molecular link from gene to late-onset retinal degeneration

December 9, 2021

Scientists have discovered that gene therapy and the diabetes drug metformin may be potential treatments for late-onset retinal degeneration (L-ORD), a rare, blinding eye disease.
Retinal pigment epithelial cells stained green and magenta

CU Researchers Provide First Evidence Linking Extracellular Vesicles with Drusen Formation and Age-Related Macular Degeneration

November 12, 2021

CellSight researchers at the University of Colorado School of Medicine are offering the first evidence connecting drusen formation, or yellowish deposits that accumulate under the retina, with extracellular vesicles and age-related macular degeneration.

Retinoid Therapy May Improve Vision in People with Rare Genetic Disorder, According to Study in Mice

November 9, 2021

Researchers have uncovered the mechanism of vision loss in Usher syndrome, yielding additional drug targets for eventual development of better therapies.